Related Experiment Video
Updated: Jan 24, 2026

Author Spotlight: Advancing Diabetes Research with Static Exercise Training in Mice
Published on: March 29, 2024
Leisure-Time Running Reduces the Risk of Incident Type 2 Diabetes.
Yuehan Wang1, Duck-Chul Lee2, Angelique G Brellenthin2
1Department of Kinesiology, Iowa State University, Ames, IA; Department of Physiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Leisure-time running significantly lowers the risk of developing type 2 diabetes in adults. Consistent dose-response relationships were found, supporting running as a preventive measure.
Area of Science:
- Exercise Physiology
- Preventive Medicine
- Endocrinology
Background:
- Type 2 diabetes is a major global health concern.
- Sedentary lifestyles contribute to the rising incidence of type 2 diabetes.
- Understanding the role of specific physical activities like running is crucial for prevention.
Purpose of the Study:
- To investigate the association between leisure-time running and incident type 2 diabetes.
- To examine the dose-response relationship between running parameters and type 2 diabetes risk.
Main Methods:
- A cohort of 19,347 adults, free of major diseases at baseline, was followed for an average of 6.5 years.
- Leisure-time running and other physical activities were self-reported.
- Type 2 diabetes incidence was determined by fasting glucose levels, physician diagnosis, or insulin use.
Main Results:
- Runners had a 28% lower risk of developing type 2 diabetes compared to non-runners.
- A significant linear dose-response relationship was observed between running time, distance, frequency, and reduced type 2 diabetes risk.
- Adjustments were made for potential confounders, including non-running aerobic physical activity.
Conclusions:
- Leisure-time running is associated with a reduced risk of developing type 2 diabetes.
- The findings support the recommendation of running as a preventive strategy for type 2 diabetes.
- Dose-response effects indicate that increased running correlates with greater risk reduction.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Types of Reports II: Incident or Occurrence Report
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Wald-Wolfowitz Runs Test II
For binary data, runs are identified using symbols such as + and −, or equivalently, 1s and 0s. In...
Wald-Wolfowitz Runs Test I
The test works...

