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Antibiotic Dereplication Using the Antibiotic Resistance Platform
Published on: October 17, 2019
[ANTIBIOTIC STEWARDSHIP IN ISRAEL - WHERE ARE WE HEADED IN 2018?]
Lior Nesher1, Jacob Strahilevitz2
1Infectious Disease Institute, Soroka Medical Center affiliated to Faculty of Health Sciences, Ben-Gurion University of the Negev.
Introduction:
We live in an age where antibiotic resistant pathogens are common, and we see an increase in infections caused by multidrug resistant pathogens. This arises from the broad use of antibiotics, many times inappropriately, combined with slackening in recent years of new antibiotic development. This combination of events threatens the core of modern medical care, increasing the number of patients with resistant infections resulting in prolonged illness with high morbidity and mortality. Most antibiotics are not prescribed by infectious disease specialists and inappropriate antibiotic use habits foster increased resistance. When prescribing an antibiotic to a patient, the physician impacts the society and environment, as well as his patient, hence the critical need for implementing antibiotic stewardship programs. The incorporation of electronic medical records into medical care in the last decade provides effective opportunities for implementing antibiotic stewardship. In this review we present the elements of antibiotic stewardship and suggest different methods for Israeli medical organizations to implement an antibiotic stewardship program. There are many different interventions that may be applied, and each institution or organization must evaluate their unique environment and challenges and implement a program that has the best possibility to succeed. There is no single program that fits all. The programs must be led by Infectious Disease specialists and management must prioritize the resources needed and continuously stay involved to keep the agenda in the forefront, so we may lead a change in our healthcare system, which is critical for our health and for the future of modern medicine.
Insights
Antibiotic resistance is a growing threat due to inappropriate use and limited new drug development. Implementing antibiotic stewardship programs, especially using electronic medical records, is crucial for combating this crisis.
Area of Science:
- Infectious Diseases
- Public Health
- Healthcare Management
Background:
- Rising prevalence of antibiotic-resistant pathogens and multidrug-resistant infections.
- Inappropriate antibiotic use and a decline in new antibiotic development exacerbate the resistance crisis.
- Threatens modern medicine, leading to increased patient morbidity and mortality.
Purpose of the Study:
- To present the essential elements of antibiotic stewardship.
- To suggest methods for implementing antibiotic stewardship programs in Israeli medical organizations.
- To emphasize the need for tailored, institution-specific approaches.
Main Methods:
- Review of existing antibiotic stewardship interventions.
- Focus on leveraging electronic medical records for stewardship.
- Highlighting the role of Infectious Disease specialists and continuous management involvement.
Main Results:
- Antibiotic stewardship programs are vital for combating resistance.
- Electronic medical records offer effective platforms for stewardship implementation.
- Successful programs require tailored interventions and strong leadership.
Conclusions:
- Antibiotic stewardship is critical for preserving modern medical care.
- Customized programs led by Infectious Disease specialists are essential for success.
- Sustained management commitment is necessary to drive systemic change in healthcare.
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