Related Experiment Video
Updated: Jan 24, 2026
08:34
Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy
Published on: September 25, 2017
25.4K
Incident Left Ventricular Hypertrophy in Masked Hypertension
Cesare Cuspidi1,2, Rita Facchetti1, Fosca Quarti-Trevano1
1From the Department of Medicine and Surgery, University of Milano-Bicocca, Italy (C.C., R.F., F.Q.-T., G.G., G.M.).
Hypertension (Dallas, Tex. : 1979)
|May 21, 2019
Summary
Masked hypertension, where office blood pressure is normal but ambulatory blood pressure is high, significantly increases the risk of developing left ventricular hypertrophy. This highlights the importance of ambulatory blood pressure monitoring for accurate cardiovascular risk assessment.
Area of Science:
- Cardiology
- Hypertension Research
- Clinical Epidemiology
Background:
- Left ventricular hypertrophy (LVH) is a significant risk factor for cardiovascular events.
- Masked hypertension (MH), characterized by normal office blood pressure but elevated ambulatory blood pressure, is increasingly recognized.
- The predictive value of MH for subclinical cardiac changes like LVH requires further investigation.
Purpose of the Study:
- To evaluate masked hypertension (MH) as a predictor of new-onset left ventricular hypertrophy (LVH).
- To assess the association between MH and the absolute increase in left ventricular mass index over 10 years.
- To determine if office blood pressure alone is sufficient for risk stratification of incident LVH.
Main Methods:
- Analysis of 803 participants from the PAMELA study without baseline LVH.
- Simultaneous measurement of clinical variables, echocardiography, office, and 24-hour ambulatory blood pressure (ABP) at baseline and 10-year follow-up.
- Classification into normotensive, masked hypertension (MH), and sustained hypertension groups based on office and ABP values.
Main Results:
- 7.1% of participants had masked hypertension (MH) at baseline.
- 22.6% of participants developed new-onset left ventricular hypertrophy (LVH) over 10 years.
- MH was significantly associated with a 2.22-fold increased risk of new-onset LVH (OR, 2.22; CI, 1.11-4.46; P=0.0250) after confounder adjustment.
- An increased absolute left ventricular mass index was also observed in MH.
Conclusions:
- Masked hypertension (MH), identified by combining office and ambulatory blood pressure (ABP) measurements, is a significant predictor of new-onset left ventricular hypertrophy (LVH).
- Office blood pressure readings alone may underestimate the risk of developing LVH in the general population.
- Ambulatory blood pressure monitoring is crucial for accurate cardiovascular risk assessment, particularly for identifying MH and preventing LVH.
More Related Videos
Related Concept Videos
01:08Prevalence and Incidence
1.7K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.7K
01:30Administering Oxygen by Mask
2.3K
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
2.3K
01:19Masking and Demasking Agents
3.5K
EDTA titrations may necessitate masking and demasking agents to temporarily protect a particular metal ion in a mixture from the EDTA reaction. These agents facilitate the sequential analysis of the metal ions by forming stable complexes with some—but not all—metal ions during certain steps.
There are many masking agents, such as cyanide, fluoride, triethanolamine, thiourea, and 2,3-bis(sulfanyl)propan-1-ol (formerly 2,3-dimercapto-1-propanol), with the masking agent chosen based on...
There are many masking agents, such as cyanide, fluoride, triethanolamine, thiourea, and 2,3-bis(sulfanyl)propan-1-ol (formerly 2,3-dimercapto-1-propanol), with the masking agent chosen based on...
3.5K
01:21Types of Reports II: Incident or Occurrence Report
1.2K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.2K
01:26Oxygen Delivering System I: Nasal Cannula and Face Mask
1.6K
The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
1.6K
01:28Hypertension I: Introduction
788
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
788