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Related Experiment Video

Updated: Jan 24, 2026

Author Spotlight: Low-Cost Electroencephalographic Recording System Combined with a Millimeter-Sized Coil to Transcranially Stimulate the Mouse Brain In Vivo

Author Spotlight: Low-Cost Electroencephalographic Recording System Combined with a Millimeter-Sized Coil to Transcranially Stimulate the Mouse Brain In Vivo

Published on: May 26, 2023

Enhancing Coil Design for Micromagnetic Brain Stimulation.

Giorgio Bonmassar¹, Laleh Golestanirad¹, Jiangdong Deng²

¹A. A. Martinos Center, Harvard Medical School, Massachusetts General Hospital, Charlestown, 02129 MA, USA.

MRS Advances

|May 21, 2019

Summary

Researchers developed advanced microscale coils for micromagnetic stimulation (μMS), enhancing neural tissue stimulation. These coils optimize magnetic flux for targeted nerve activation, paving the way for future brain and heart stimulators.

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Published on: August 20, 2019

Area of Science:

Biomedical Engineering
Neurotechnology
Electromagnetics

Background:

Micromagnetic stimulation (μMS) uses magnetic induction for focal neural tissue stimulation via sub-millimeter coils.
Existing μMS devices often use commercial inductors not optimized for neural tissue magnetic field delivery.
There is a need for improved coil designs to enhance the efficacy and precision of μMS.

Purpose of the Study:

To design and fabricate advanced microscale coil structures for next-generation μMS devices.
To optimize magnetic flux injection into neural tissue for improved stimulation.
To investigate the electric field distribution and potential for targeted neuronal activation.

Main Methods:

Fabrication of microscale coil structures with a planar square spiral geometry.
Electromagnetic Finite Elements Method (FEM) simulations to analyze device performance.
Evaluation of magnetic flux distribution and induced electric fields in simulated neural tissue.

Main Results:

The planar square spiral coil design optimizes magnetic flux delivery to the tissue.
FEM simulations revealed an asymmetry in the induced electric field despite the symmetric coil design.
This asymmetry shows potential for activating neurons with specific axonal orientations.

Conclusions:

The developed microscale coils represent an advancement in μMS technology.
The asymmetric induced electric field offers a novel mechanism for precise neuronal activation.
These findings support the potential of μMS devices as future contactless brain and heart stimulators for various neurological conditions.