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Updated: Jan 24, 2026

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
Published on: April 4, 2022
Selective recognition of acetylcholine over choline by a fluorescent cage
Augustin Long1, Nicolas Fantozzi, Sandra Pinet
1Aix Marseille Université, Centrale Marseille, CNRS, ISM2 UMR 7313, 13397, Marseille, France. alexandre.martinez@centrale-marseille.fr.
Abstract:
A fluorescent hemicryptophane has been synthesized and can be used as a turn on receptor of acetylcholine. A binding constant of 2.4 × 104 M-1 was measured for this neurotransmitter, and its selective and sensitive detection over choline and choline phosphate was achieved. NMR and DFT calculations provide insight into the interactions involved in this selective recognition process.
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