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Updated: Jan 24, 2026

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
Published on: August 19, 2012
[Advances in m 6A modification and its regulation of viral replication]
Peng Xue1, Tao Jiang1, Xing Jia Shen1,2
1Jiangsu Key Laboratory of Sericutural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China.
Abstract:
N 6-methyladenosine (m 6A) is a prevalent modification of RNA in eukaryotes and plays an important role in the process of mRNA translocation, stabilization and translation. m 6A exerts different influences on the viral replication cycle, and both viral replication and host immune response to the virus are affected by m 6A. In this review, we summarize recent studies on the mechanism of m 6A modification and its effects on viral replication and host immune response, in order to provide a reference for epigenetic regulation in the viral life cycle.
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