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Ontogenetic and Pathogenetic Views on Somatic Chromosomal Mosaicism

Ivan Y Iourov1,2, Svetlana G Vorsanova3,4, Yuri B Yurov5,6

  • 1Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, 117152 Moscow, Russia. ivan.iourov@gmail.com.

Genes
|May 22, 2019
PubMed
Summary

Chromosomal mosaicism, or cell karyotype variation, is linked to human diseases. Advanced genomic technologies now enable better detection and understanding of its role in health and disease.

Keywords:
aneuploidychromosomal instabilitychromosomechromosome heterogeneitygenome instabilitygenomic variationssomatic mosaicism

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