Related Experiment Video
Updated: Jan 24, 2026
02:30
Endoscopic Approach for Colloid Cyst Resection
Published on: May 23, 2025
734
Clips for managing perforation and bleeding after colorectal endoscopic mucosal resection
A S Turan1, G Ultee1, E J M Van Geenen1
1a Department of Gastroenterology and Hepatology , Radboud University Medical Centre , The Netherlands.
Expert Review of Medical Devices
|May 22, 2019
Summary
Endoscopic mucosal resection (EMR) clips effectively treat and prevent complications like bleeding and perforation after colorectal adenoma removal. Future advancements in clipping techniques and technologies like endoscopic full-thickness resection (eFTR) will further refine EMR practices.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Colorectal Cancer Screening
Background:
- Endoscopic mucosal resection (EMR) is the primary treatment for advanced colorectal adenomas.
- Increased colorectal cancer screening has led to more EMR procedures and associated complications.
- Clips are crucial for managing bleeding and perforation risks post-EMR.
Purpose of the Study:
- To review the current applications of clips in treating and preventing EMR complications.
- To evaluate the historical development and properties of endoscopic clips.
- To discuss evolving clipping techniques and their impact on future endoscopic practices.
Main Methods:
- Literature review of therapeutic and prophylactic clipping for EMR complications.
- Evaluation of historical clip development and properties.
- Discussion of various clipping techniques and their efficacy in wound closure.
- Highlighting emerging technologies like endoscopic full-thickness resection (eFTR).
Main Results:
- Prophylactic clipping is most researched for delayed bleeding after large adenoma EMR.
- Optimal clip spacing is recommended at 0.5-1.0 cm for aligning clips.
- Endoscopic clipping may increasingly replace surgery for perforations.
- New technologies like eFTR are expected to influence future clip utilization.
Conclusions:
- Clips are essential tools for managing EMR-related bleeding and perforation.
- Advancements in clip technology and techniques, including eFTR, will shape future endoscopic interventions.
- The focus of research may shift towards perforation management with endoscopic clips.
Related Concept Videos
01:28Esophageal Perforation-II: Clinical Manifestations and Management
575
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
575
01:22Bleeding in Fresh Concrete
560
Bleeding in fresh concrete occurs when water from the mix rises to the surface. This happens because the mix's solid components fail to retain all the water as they settle, leading to separation where water collects at the top. The severity of bleeding can be measured by assessing the total settlement or by noting the decrease in height per unit height of concrete.
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
560
01:22Esophageal Perforation-I: Introduction
480
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
480
01:25Mucosal Barrier of the Stomach
2.1K
The gastric glands contain parietal cells that secrete hydrochloric acid (HCl) for digestion. The cells secrete HCl because it is highly corrosive and essential for breaking down food. To achieve this, they secrete hydrogen and chloride ions into the lumen of the gastric glands, which combine to form HCl.
Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...
Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...
2.1K
01:26Endoscopic Studies II: Thoracocentesis
1.3K
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
1.3K
01:29Endoscopic Procedures I: Esophagogastroduodenoscopy
1.0K
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
1.0K