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Vagus Nerve Stimulation and the Cardiovascular System
Michael J Capilupi1, Samantha M Kerath2, Lance B Becker1,2,3
1Department of Emergency Medicine, North Shore University Hospital, Northwell Health, Manhasset, New York 11030.
Cold Spring Harbor Perspectives in Medicine
|May 22, 2019
Summary
Vagus nerve stimulation (VNS) shows promise for treating various diseases, including cardiovascular disorders. Research reviews preclinical and clinical studies on VNS
Area of Science:
- Cardiovascular physiology and neuroscience.
Background:
- The vagus nerve is crucial for maintaining physiological balance and regulating cardiac function.
- Vagus nerve activity correlates with heart rate variability (HRV), indicating its role in vagal tone.
Purpose of the Study:
- To review current preclinical and clinical research on vagus nerve stimulation (VNS).
- To explore the potential applications of VNS in cardiovascular disorders.
Main Methods:
- Review of existing scientific literature on VNS and cardiovascular health.
- Analysis of preclinical and clinical study outcomes.
Main Results:
- VNS is being investigated for conditions like epilepsy, arthritis, Crohn's disease, and asthma.
- The vagus nerve's cardiac innervation makes VNS a potential therapy for cardiac arrest, myocardial infarction, and stroke.
Conclusions:
- VNS holds significant potential as a therapeutic strategy for cardiovascular diseases.
- Further research into VNS applications for cardiovascular health is warranted.
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