Related Experiment Video For argatroban
Updated: Jan 24, 2026

Network Pharmacology Prediction and Experimental Validation of Trichosanthes-Fritillaria thunbergii Action Mechanism Against Lung Adenocarcinoma
Published on: March 3, 2023
A hypercoagulable state leading to venous limb gangrene associated with occult lung adenocarcinoma
Matthew M A Waite1, Anthony W Martinelli2, Stephen D Preston2
1Addenbrooke's Hospital University of Cambridge School of Clinical Medicine Cambridge UK.
Abstract:
We report a case of lung adenocarcinoma-associated hypercoagulability leading to venous limb gangrene, managed successfully with argatroban and then dabigatran. Use of idarucizumab permitted diagnostic investigations, leading to targeted antineoplastic therapy with crizotinib, surgical resection with curative intent, and continued survival over 2 years after the index event.
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