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Updated: Jan 24, 2026

Using the GELFREE 8100 Fractionation System for Molecular Weight-Based Fractionation with Liquid Phase Recovery
Published on: December 3, 2009
Using Fractionation and Diffusion Ordered Spectroscopy to Study Lignin Molecular Weight
James R D Montgomery1, Priory Bazley1, Tomas Lebl1
1School of Chemistry and Biomedical Sciences Research Complex University of St Andrews and EaStCHEM St Andrews, Fife KY16 9ST UK.
Abstract:
Recent reports demonstrate that applications of the biopolymer lignin can be helped by the use of a fraction of the lignin which has an optimal molecular weight range. Unfortunately, the current methods used to determine lignin's molecular weight are inconsistent or not widely accessible. Here, an approach that relies on 2D DOSY NMR analysis is described that provides a measure of lignin's molecular weight. Consistent results were obtained using this well-established NMR technique across a range of lignins.
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