Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Allogeneic bone marrow transplantation in multiple myeloma.

A Gallamini, F Buffa, A Bacigalupo

    Acta Haematologica
    |January 1, 1987
    PubMed
    Summary

    This study details a successful case of allogeneic bone marrow transplantation (BMT) for Bence-Jones multiple myeloma (MM). The patient achieved complete remission, highlighting BMT as a viable treatment for advanced multiple myeloma.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A prospective study with Comprehensive Geriatric Assessment (CGA) before curative treatment in older patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC).

    Oral oncology·2026
    Same author

    Validation of a prognostic nomogram for locally advanced oropharyngeal carcinoma treated with intensity-modulated radiotherapy with/without systemic therapy.

    ESMO open·2025
    Same author

    KEYNOTE-689: A step forward or a leap of faith in resectable LA-HNSCC?

    Oral oncology·2025
    Same author

    Effect of HLA mismatch on post-transplant infections in allogeneic hematopoietic stem cell transplantation with PTCy-based GvHD prophylaxis.

    Bone marrow transplantation·2023
    Same author

    Cord blood resilience in a patient with relapsing Ph + B lymphoblastic acute leukemia after hematopoietic stem cell transplantation.

    Annals of hematology·2022
    Same author

    Chemo- immunotherapy and radiation in locally advanced head and neck cancer: Where do we stand?

    Oral oncology·2022

    Area of Science:

    • Hematology
    • Oncology
    • Stem Cell Transplantation

    Background:

    • Multiple myeloma (MM) is a hematologic malignancy characterized by uncontrolled proliferation of plasma cells.
    • Bence-Jones multiple myeloma, a subtype, presents with osteolytic lesions and bone marrow infiltration.
    • Allogeneic bone marrow transplantation (BMT) is a potential curative treatment for eligible MM patients.

    Observation:

    • A 28-year-old woman with Bence-Jones MM presented with extensive osteolytic lesions and bone marrow plasmacytosis.
    • Following 6 cycles of melphalan and prednisone chemotherapy, the patient achieved clinical remission.
    • The patient underwent allogeneic BMT from a matched sibling donor.

    Findings:

    • The patient has been monitored for 23 months post-BMT.

    Related Experiment Videos

  • Complete remission was confirmed by both clinical and laboratory assessments.
  • This case adds to the literature on BMT efficacy in multiple myeloma.

    • Implications:

    • Allogeneic BMT can lead to durable complete remission in patients with advanced multiple myeloma.
    • This treatment approach warrants consideration for select MM patients.
    • Further research into BMT protocols for multiple myeloma is encouraged.