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Does CHA2DS2-VASc Score Predict MACE in Patients Undergoing Isolated Coronary Artery Bypass Grafting Surgery?

Muhsin Kalyoncuoglu1, Semi Ozturk1, Mazlum Sahin2

  • 1Haseki Training and Research Hospital Department of Cardiology Istanbul Turkey Department of Cardiology, Haseki Training and Research Hospital, Istanbul, Turkey.

Brazilian Journal of Cardiovascular Surgery
|May 22, 2019
PubMed

Insights

The CHA2DS2-VASc score can predict major adverse cardiac events (MACE) in patients undergoing isolated coronary artery bypass grafting (CABG). This score offers valuable prognostic insight for CABG patients, aiding in risk stratification and clinical decision-making.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Clinical Risk Stratification

Background:

  • Coronary artery bypass grafting (CABG) is a common procedure for severe coronary artery disease.
  • Accurate prediction of major adverse cardiac events (MACE) post-CABG is crucial for patient management.
  • The prognostic utility of the CHA2DS2-VASc score in isolated CABG patients remains to be fully elucidated.

Purpose of the Study:

  • To evaluate the prognostic value of the CHA2DS2-VASc score in predicting MACE after isolated CABG surgery.
  • To compare the predictive accuracy of CHA2DS2-VASc score with other established risk scores.

Main Methods:

  • Retrospective review of 464 patients undergoing elective isolated CABG.
  • Patients were stratified into low (<2) and high (≥2) CHA2DS2-VASc score groups.
  • Univariate logistic regression and receiver-operating characteristic (ROC) curve analysis were used to assess MACE prediction.

Main Results:

  • Higher CHA2DS2-VASc scores were associated with increased prevalence of comorbidities like hypertension and diabetes.
  • Patients with high CHA2DS2-VASc scores exhibited significantly higher rates of in-hospital mortality and MACE.
  • CHA2DS2-VASc score demonstrated strong specificity (84.1%) in predicting MACE, with comparable accuracy to SYNTAX II-CABG score.

Conclusions:

  • The CHA2DS2-VASc score is a valuable and specific predictor of MACE in patients undergoing isolated CABG.
  • This score can aid clinicians in risk stratification and optimizing perioperative management for CABG patients.
Abstract

Keywords:
Coronary Artery Bypass – adverse effectsCoronary Artery DiseaseLenght of Stay – trendsTime Factors

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