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Multiple myeloma presenting with primary meningococcal arthritis
The American Journal of Medicine
|June 1, 1987
Abstract:
A 64-year-old white man presented with Neisseria meningitidis primary septic arthritis. Further evaluation revealed multiple myeloma. Increased susceptibility to infection occurs early in multiple myeloma; thus, a rare cause of primary septic arthritis, such as N. meningitidis, warrants a full evaluation for immunocompromise.
Insights
A rare Neisseria meningitidis septic arthritis case in a 64-year-old man led to a multiple myeloma diagnosis. This highlights the need to investigate immunocompromise in patients with unusual infections.
Area of Science:
- Infectious Diseases
- Hematology
- Immunology
Background:
- Multiple myeloma is a hematologic malignancy associated with increased infection risk.
- Septic arthritis is a serious joint infection that can be caused by various pathogens.
Observation:
- A 64-year-old male presented with primary septic arthritis caused by Neisseria meningitidis.
- Subsequent investigations revealed a concurrent diagnosis of multiple myeloma.
Findings:
- Neisseria meningitidis is an uncommon cause of primary septic arthritis.
- The presence of this pathogen suggests an underlying immunocompromised state.
Implications:
- Patients with multiple myeloma are susceptible to opportunistic infections.
- Rare infectious agents like Neisseria meningitidis in septic arthritis warrant thorough evaluation for underlying immunocompromise, such as multiple myeloma.