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Clinical Significance of Incidental Rolandic Spikes in Children With Absence Epilepsy
Anita N Datta1,2, Laura Wallbank2, Jeremy C H Mak3
11 Department of Pediatrics, Division of Neurology, BC Children's Hospital, Vancouver, BC, Canada.
Journal of Child Neurology
|May 23, 2019
Summary
Children with absence epilepsy and rolandic spikes showed more developmental and language delays. These findings suggest rolandic spikes may indicate additional cognitive challenges in absence epilepsy patients.
Area of Science:
- Pediatric Neurology
- Epileptology
Background:
- Absence epilepsy and benign epilepsy of childhood with central temporal spikes are common childhood epilepsy syndromes.
- The co-occurrence of 3-Hz generalized spike-wave discharges and rolandic spikes is rare.
Purpose of the Study:
- To compare clinical features of absence epilepsy patients with and without rolandic spikes.
- To determine the clinical significance of co-occurring rolandic spikes in absence epilepsy.
Main Methods:
- Retrospective analysis of clinical data.
- Comparison of 17 children with absence epilepsy and rolandic spikes to 90 age-matched controls with absence epilepsy.
Main Results:
- Patients with absence epilepsy and rolandic spikes showed significantly higher rates of global developmental delay (29% vs 6%) and expressive language delay (24% vs 6%).
- Difficulties with school performance, particularly language-related tasks, were more prevalent in the group with rolandic spikes (35% vs 6%).
- No significant differences were found in anxiety, behavioral issues, mood disorders, or ADHD between the groups.
Conclusions:
- The presence of rolandic spikes in absence epilepsy is associated with increased epilepsy comorbidities.
- Rolandic spikes may serve as a marker for additional cognitive and language challenges in children with absence epilepsy.
- Physicians should consider these potential comorbidities when managing absence epilepsy patients with rolandic spikes.
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