Related Experiment Video
Updated: Jan 24, 2026

Clinical Practice Protocol of Creative Music Therapy for Preterm Infants and Their Parents in the Neonatal Intensive Care Unit
Published on: January 7, 2020
Improved Outcomes With Standardized Convalescent Preterm Respiratory Care Practices
Michelle D Tyler1, Neetu Singh2, Matthew J McNally3
1Division of Neonatology, Department of Pediatrics, Children's Hospital at Dartmouth, and the Leadership Preventive Medicine Residency, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. michelle.d.tyler@hitchcock.org.
Insights
Improving respiratory care for very low birthweight (VLBW) infants significantly reduced the need for home oxygen. This quality improvement project in a neonatal ICU lowered discharge rates on oxygen and chronic lung disease in VLBW infants.
Area of Science:
- Neonatal Medicine
- Pediatric Pulmonology
- Quality Improvement Science
Background:
- Chronic lung disease is a major complication for very low birthweight (VLBW) infants.
- Discharge home on oxygen imposes substantial burdens on families.
- Current convalescent respiratory practices require optimization to reduce oxygen dependency.
Purpose of the Study:
- To decrease the proportion of VLBW infants discharged home requiring supplemental oxygen.
- To enhance respiratory outcomes in VLBW infants through improved care practices.
Main Methods:
- A prospective quality improvement initiative was conducted in a neonatal intensive care unit (NICU).
- Interventions included a room air challenge, oxygen reference chart, and standardized oxygen delivery guidelines, implemented via Plan-Do-Study-Act cycles.
- Statistical process control charts monitored primary and secondary outcomes, including chronic lung disease rates and time off respiratory support.
Main Results:
- The percentage of VLBW infants discharged on oxygen decreased significantly from 34.4% to 18.5% and 21.7% in subsequent years.
- The incidence of chronic lung disease also saw a reduction from 31.2% to 25.4%.
- Key metrics such as discharge age, weight, and readmission rates remained stable.
Conclusions:
- Standardizing convalescent respiratory care effectively improved respiratory morbidity in VLBW infants.
- These evidence-based interventions offer a model for other NICUs facing similar challenges.
- Optimizing respiratory care can reduce long-term complications and family burden in preterm infants.
Background:
Chronic lung disease is the most common morbidity affecting very low birthweight (VLBW) infants. Many of these infants are discharged home on oxygen, placing significant emotional and financial burdens on families. We sought to reduce the proportion of VLBW infants requiring discharge home on oxygen by improving convalescent respiratory practices.
Methods:
We performed a prospective quality-improvement project for infants with birth weights ≤ 1,500 g in a single neonatal ICU. Using Plan-Do-Study-Act cycles, we developed and implemented a room air challenge, oxygen reference chart, and a standardized oxygen delivery guideline. The primary outcome was the proportion of VLBW infants discharged home on oxygen. Secondary outcomes included rate of chronic lung disease and postmenstrual age when off all respiratory support. Balancing measures were postmenstrual age and weight at discharge, as well as unplanned readmissions. Statistical process control charts were used to monitor outcomes and balancing measures.
Results:
The proportion of VLBW infants discharged home on oxygen decreased from 34.4% to 18.5% and 21.7% in the following two years (P = .044 and P = .01, respectively). G-Chart analysis showed a higher mean number of successes between failures. The rate of chronic lung disease decreased from 31.2% to 25.4% (P = .03). The mean postmenstrual age at discharge, mean weight at discharge, and readmission rate were unchanged.
Conclusion:
Standardization of convalescent respiratory care practices improved respiratory morbidities in VLBW infants. These interventions could be utilized in other NICUs with high incidence of respiratory morbidities despite improvement in delivery room practices.
Related Concept Videos
Standards of Care II
Standards of Care I
Predicting Reaction Outcomes
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Anatomy of Respiratory System II: Lower Respiratory Tract
The Larynx
It is located between the pharynx and the trachea, acts as a passageway for air, and hosts several critical structures, such as the epiglottis, vocal cords, and glottis. The epiglottis acts as a gateway, guiding food to the...
The Respiratory System

