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Updated: Jan 24, 2026
Extraction of Aqueous Metabolites from Cultured Adherent Cells for Metabolomic Analysis by Capillary Electrophoresis-Mass Spectrometry
Published on: June 9, 2019
A NOTCH added to metabolomics
1Section of Oncology, Drammen Hospital, Vestre Viken Health Trust, Dronninggata 28, N-3004, Drammen, Norway. otr@vestreviken.no.
Abstract:
Deregulated metabolism is a hallmark of cancer. In the accompanying study by Sellers et al. published in the British Journal of Cancer, metabolism-related transcriptomics data from in silico data sets are analysed, with the findings being further investigated in the experiments on tumour tissue slices and finally validated in patients. The study adds to our growing understanding of therapeutically accessible metabolic reprogramming in malignancies.
Insights
Cancer cells exhibit altered metabolism. This study analyzes metabolism data to understand cancer
Area of Science:
- Oncology
- Cancer Metabolism
- Transcriptomics
Background:
- Altered cellular metabolism is a key characteristic of cancer.
- Metabolic reprogramming is increasingly recognized as a potential therapeutic target in oncology.
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