Jove
Visualize
Contact Us

Related Concept Videos

Ranks01:02

Ranks

476
Unlike parametric methods, nonparametric statistics are ideal for nominal and ordinal data, requiring fewer assumptions about the population's nature or distribution. This makes nonparametric methods easier to apply and interpret, as they do not depend on parameters like mean or standard deviation. One common approach in nonparametric analysis is to sort data according to a specific criterion. For instance, we might arrange weather data from hottest to coldest days in a month or rank cities...
476
Spearman's Rank Correlation Test01:20

Spearman's Rank Correlation Test

1.5K
Spearman's rank correlation test, also known as Spearman's rho, is a nonparametric method for assessing the strength and direction of association between two variables. This test is particularly valuable when the data distribution is unknown or when the assumption of normality does not hold. Named after the English psychologist and statistician Dr. Charles Edward Spearman, it serves as the nonparametric counterpart to Pearson's correlation coefficient.
Spearman's test calculates correlation by...
1.5K
Wilcoxon Rank-Sum Test01:21

Wilcoxon Rank-Sum Test

734
The Wilcoxon rank-sum test, also known as the Mann-Whitney U test, is a nonparametric test used to determine if there is a significant difference between the distributions of two independent samples. This test is designed specifically for two independent populations and has the following key requirements:
734
Friedman Two-way Analysis of Variance by Ranks01:21

Friedman Two-way Analysis of Variance by Ranks

497
Friedman's Two-Way Analysis of Variance by Ranks is a nonparametric test designed to identify differences across multiple test attempts when traditional assumptions of normality and equal variances do not apply. Unlike conventional ANOVA, which requires normally distributed data with equal variances, Friedman's test is ideal for ordinal or non-normally distributed data, making it particularly useful for analyzing dependent samples, such as matched subjects over time or repeated measures...
497
The Mantel-Cox Log-Rank Test01:19

The Mantel-Cox Log-Rank Test

1.0K
The Mantel-Cox log-rank test is a widely used statistical method for comparing the survival distributions of two groups. It tests whether a statistically significant difference exists in survival times between the groups without assuming a specific distribution for the survival data, making it a non-parametric test. This flexibility makes the log-rank test particularly valuable in medical research and other fields where the timing of an event, such as death or disease recurrence, is of...
1.0K
Wilcoxon Signed-Ranks Test for Matched Pairs01:09

Wilcoxon Signed-Ranks Test for Matched Pairs

489
The Wilcoxon signed-rank test for matched pairs evaluates the null hypothesis by combining the ranks of differences with their signs. It essentially tests whether the median of the differences in a population of matched pairs is zero. Since the test incorporates more information than the sign test, it generally yields more trustable conclusions. This test also does not require the data to follow a normal distribution, but two conditions must be met for it to be applicable: (1) the data must...
489

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MARCKS as a mediator and target for pathological tunneling nanotubes between patient-derived glioblastoma cells and astrocytes.

Cell death & disease·2026
Same author

MondrianMap: Navigating Gene Set Hierarchies with Multi-Resolution Enrichment Maps.

bioRxiv : the preprint server for biology·2026
Same author

A genome-scale CRISPRi perturbation atlas of human induced pluripotent stem cells.

Nature biotechnology·2026
Same author

Randomized, double-blind, sham-controlled trial of an intraoral photobiomodulation device for oral mucositis and associated complications due to radiotherapy for head and neck cancer.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026
Same author

Challenges of using AI-based synthetic data in health economics and outcomes research.

Expert review of pharmacoeconomics & outcomes research·2026
Same author

Design and Development of a Novel LXRβ/PPARδ Dual Agonist for Memory Impairment and Pathology in 3xTg-AD Animal Model of Alzheimer's Disease.

ACS chemical biology·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jan 24, 2026

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications
09:20

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

Published on: February 23, 2019

9.2K

BEERE: a web server for biomedical entity expansion, ranking and explorations.

Zongliang Yue1, Christopher D Willey2, Anita B Hjelmeland3

  • 1Informatics Institute, School of Medicine, the University of Alabama at Birmingham, AL 35233, USA.

Nucleic Acids Research
|May 23, 2019
PubMed
Summary

BEERE is a free web tool for biomedical researchers to analyze gene and protein lists. It helps characterize biomedical entities, rank their importance, and visualize relationships to generate new hypotheses.

More Related Videos

Synthesis of Keratin-based Nanofiber for Biomedical Engineering
14:43

Synthesis of Keratin-based Nanofiber for Biomedical Engineering

Published on: February 7, 2016

15.9K
Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

1.4K

Related Experiment Videos

Last Updated: Jan 24, 2026

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications
09:20

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

Published on: February 23, 2019

9.2K
Synthesis of Keratin-based Nanofiber for Biomedical Engineering
14:43

Synthesis of Keratin-based Nanofiber for Biomedical Engineering

Published on: February 7, 2016

15.9K
Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

1.4K

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Biomedical researchers need tools to analyze complex gene and protein datasets.
  • Characterizing biomedical entities and their relationships is crucial for hypothesis generation.

Purpose of the Study:

  • To introduce BEERE (Biomedical Entity Expansion, Ranking and Explorations), a novel web-based tool.
  • To enable researchers to analyze lists of biomedical entities within the context of existing literature.
  • To facilitate the examination of entity relationships, ranking, and hypothesis generation.

Main Methods:

  • BEERE analyzes user-provided lists of genes, proteins, or biomedical terms.
  • It assesses the credibility of known entity-to-entity relationships using literature and databases.
  • The tool computes ranking scores to determine the relative importance of each entity.

Main Results:

  • BEERE provides a list of original and expanded entities with associated relationship data.
  • It reports statistically significant ranks and scores for each entity.
  • An interactive network visualization displays entity relationships with data provenance.

Conclusions:

  • BEERE offers a comprehensive solution for biomedical data analysis and exploration.
  • The tool aids in uncovering novel gene functions and genotype-phenotype associations.
  • Its free, open-access web interface supports hypothesis generation for researchers.