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Updated: Jan 24, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Eleven New Triterpenoid Glycosides from the Roots of Ilex asprella
Xiao-Jun Huang1,2, Si Wen1,2, Xi-Feng Guan1,2
1Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou, 510632, P. R. China.
Abstract:
Asprellosides A-K, nine new ursane-type triterpenoid glycosides (1-9), and two new oleanane-type triterpenoid glycosides (10 and 11), including six rare sulfated triterpenoid glycosides, were isolated from the roots of Ilex asprella. Their structures were determined on the basis of comprehensive spectroscopic analysis and chemical methods. Among these compounds, asprelloside B (2) and asprelloside C (3) are the first examples of triterpenoid glycosides bearing a rare 3,4-O-disulfo-xylopyranosyl residue. All the saponins isolated showed no significant effects against respiratory syncytial virus (RSV) and lipopolysaccharide-induced nitric oxide production in Raw264.7 macrophages.
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