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Updated: Jan 24, 2026

Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi
Published on: October 5, 2018
Inbreeding depression causes reduced fecundity in Golden Retrievers
Erin T Chu1, Missy J Simpson2, Kelly Diehl2
1Embark Veterinary, Inc., 184 Lincoln St, 6th Floor, Boston, MA, 02111, USA. chue@embarkvet.com.
Abstract:
Inbreeding depression has been demonstrated to impact vital rates, productivity, and performance in human populations, wild and endangered species, and in recent years, the domestic species. In all cases, standardized, high-quality phenotype data on all individuals are invaluable for longitudinal analyses such as those required to evaluate vital rates of a study cohort. Further, many investigators agree upon the preference for and utility of genomic measures of inbreeding in lieu of pedigree-based estimates of inbreeding. We evaluated the association of measures of reproductive fitness in 93 Golden Retrievers enrolled in the Golden Retriever Lifetime Study with a genomic measurement of inbreeding, FROH. We demonstrate a statistically significant negative correlation between fecundity and FROH. This work sets the stage for larger scale analyses to investigate genomic regions associated with fecundity and other measures of fitness.
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