Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Classifying Matter by State02:49

Classifying Matter by State

102.8K
Chemistry is the study of matter and the changes it undergoes. Matter is anything that has mass and occupies space. Matter is all around us; the air, water, soil, mountains, even our bodies are all examples of matter. Matter is divided into three states — solid, liquid, and gas — that are commonly found on earth. The fourth state of matter, plasma, occurs naturally in the interiors of stars. 
102.8K
Reliability and Validity01:29

Reliability and Validity

13.8K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
13.8K
Classifying Matter by Composition03:35

Classifying Matter by Composition

90.0K
Matter: Pure Substances and Mixtures
According to its composition, the matter can be classified into two broad categories — pure substances and mixtures. 
A pure substance is a form of matter that has a constant composition throughout with uniform properties. For example, any sample of sucrose has the same composition and same physical properties, such as melting point, color, and sweetness, regardless of the source from which it is isolated. 
A mixture is composed of two or...
90.0K
Physical and Chemical Properties of Matter02:57

Physical and Chemical Properties of Matter

165.8K
The characteristics that enable us to distinguish one substance from another are called properties.
165.8K
Compounds Essential to Human Function01:25

Compounds Essential to Human Function

10.1K
The human body is composed of cells that are fundamentally made up of several different molecules. These molecules are essential to carry out all physiological processes in the body and are broadly classified into organic and inorganic based on their chemical structures.
Inorganic Compounds Essential to Human Functioning
Inorganic compounds essential to human functioning include water, salts, acids, and bases. These compounds are inorganic, i.e., they do not have a carbon-hydrogen bond. Water...
10.1K
The Atomic Theory of Matter02:59

The Atomic Theory of Matter

127.2K
The earliest recorded discussion of the basic structure of matter comes from ancient Greek philosophers. Leucippus and Democritus argued that all matter was composed of small, finite particles that they called atomos, meaning “indivisible.” Later, Aristotle and others came to the conclusion that matter consisted of various combinations of the four “elements” — fire, earth, air, and water — and could be infinitely divided. Interestingly, these philosophers...
127.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inhibition of Raly promotes oligodendrocyte precursor cell differentiation and remyelination after chronic hypoperfusion.

Neural regeneration research·2026
Same author

High-Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor.

MedComm·2026
Same author

Efficacy and safety of edaravone sublingual tablet for patients with cerebral small vessel disease-related cognitive impairment: study protocol for a multicentre, randomised, double-blind, placebo-controlled trial.

Stroke and vascular neurology·2026
Same author

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

A Nature-Inspired Steroid-like Electron Acceptor to Polarity-Dependent Probe for Visualizing Lipid Evolution in Alzheimer's Disease.

ACS nano·2025
Same author

A Surface-Engineered Microfluidic Platform with Algorithmic Optimization for Plasma Biomarker Detection in Alzheimer's Disease.

ACS sensors·2025

Related Experiment Video

Updated: Jan 24, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.8K

No reliable gray matter changes in essential tremor.

Rong Luo1,2, PingLei Pan2,3, Yun Xu4,5,6

  • 1Department of Neurology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, No. 321 Zhongshan Road, Nanjing, Jiangsu Province, 210008, People's Republic of China.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|May 23, 2019
PubMed
Summary
This summary is machine-generated.

This meta-analysis found no consistent brain gray matter (GM) changes in essential tremor (ET) using voxel-based morphometry (VBM). Heterogeneity in findings suggests variability in ET or VBM methods, limiting its diagnostic use.

Keywords:
Coordinate-based meta-analysisEssential tremorGray matterVoxel-based morphometry

More Related Videos

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
05:18

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters

Published on: July 12, 2024

702
Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy
03:59

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy

Published on: January 10, 2019

7.7K

Related Experiment Videos

Last Updated: Jan 24, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.8K
Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
05:18

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters

Published on: July 12, 2024

702
Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy
03:59

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy

Published on: January 10, 2019

7.7K

Area of Science:

  • Neuroimaging
  • Neurology
  • Quantitative analysis

Background:

  • Voxel-based morphometry (VBM) has been utilized to investigate gray matter (GM) alterations in essential tremor (ET) for over a decade.
  • Existing literature presents heterogeneous findings regarding GM changes in ET patients.

Purpose of the Study:

  • To synthesize findings from VBM studies using a coordinate-based meta-analysis.
  • To identify reliable brain GM alterations in ET patients compared to healthy controls.

Main Methods:

  • A meta-analysis of 16 VBM studies.
  • Inclusion of 387 ET patients and 355 healthy controls.
  • Meta-regression analyses to explore sources of heterogeneity.

Main Results:

  • No robust or reliable regional brain GM alterations were detected in ET patients.
  • Meta-regression identified moderators like MR field strength, statistical methods, and clinical factors contributing to heterogeneity.
  • Significant heterogeneity was observed across studies.

Conclusions:

  • High heterogeneity in GM alterations may stem from true variability in ET (clinical, etiological, pathological) or VBM methodological differences.
  • Current VBM findings are limited in reliably distinguishing ET from healthy controls.
  • Future research should focus on larger sample sizes, ET phenotyping, standardized protocols, and data sharing to improve reproducibility.