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Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery SALLI MRI in Rats
Published on: July 19, 2013
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Feasibility study of highly accelerated phase-sensitive inversion recovery myocardial viability imaging using
Zhehao Zhang1,2, Wenbo Sun3, Lan Lan3
1Institute for Medical Imaging Technology, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Journal of Magnetic Resonance Imaging : JMRI
|May 23, 2019
Summary
Simultaneous multislice (SMS) and parallel imaging (PI) accelerate cardiac MRI for myocardial viability assessment. This technique significantly reduces scan times while maintaining comparable image quality to conventional methods.
Area of Science:
- Cardiovascular Magnetic Resonance Imaging
- Myocardial Viability Assessment
- Advanced Imaging Techniques
Background:
- Phase-sensitive inversion recovery (PSIR) is crucial for cardiac MRI, enabling accurate myocardial viability assessment.
- PSIR effectively eliminates background phase and preserves magnetization signals during inversion recovery.
Purpose of the Study:
- To significantly shorten acquisition times for myocardial viability imaging.
- To integrate simultaneous multislice (SMS) and parallel imaging (PI) into PSIR without requiring additional calibration scans.
Main Methods:
- Prospective study involving a high-resolution phantom and 18 patients.
- Comparison of conventional PSIR, SMS-PSIR (2x acceleration), and SMS+PI-PSIR (4x acceleration) using a 3T segmented fast spoiled gradient echo sequence.
- Evaluation of image quality, artifact levels, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and infarct size.
Main Results:
- SMS-PSIR preserved SNR and CNR in phantom studies; SMS+PI-PSIR showed reduced SNR/CNR.
- In vivo image quality and artifact scores were comparable across all methods (P=0.20 and P=0.22, respectively).
- SMS-PSIR and SMS+PI-PSIR reduced acquisition time by 70% and 83%, respectively, compared to conventional PSIR, with comparable infarct size measurements.
Conclusions:
- SMS can be implemented in PSIR without extra calibration, maintaining image quality while drastically reducing scan time.
- The integration of PI with SMS further accelerates the imaging process.
- This accelerated PSIR technique offers a promising solution for efficient myocardial viability assessment.
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