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Updated: Jan 24, 2026

Generation and Assembly of Virus-Specific Nucleocapsids of the Respiratory Syncytial Virus
Published on: July 27, 2021
A Contemporary View of Respiratory Syncytial Virus (RSV) Biology and Strain-Specific Differences
Mansi C Pandya1, Sean M Callahan2, Kyryll G Savchenko3
1Department of Biological Sciences, Butler University, Indianapolis, IN 46208, USA. mpandya@butler.edu.
Abstract:
Respiratory syncytial virus (RSV) is a human respiratory pathogen which remains a leading viral cause of hospitalizations and mortality among infants in their first year of life. Here, we review the biology of RSV, the primary laboratory isolates or strains which have been used to best characterize the virus since its discovery in 1956, and discuss the implications for genetic and functional variations between the established laboratory strains and the recently identified clinical isolates.
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