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A Factor Two Improvement in High-Field Dynamic Nuclear Polarization from Gd(III) Complexes by Design
Gabriele Stevanato1, Dominik Józef Kubicki1, Georges Menzildjian1
1Laboratory of Magnetic Resonance, Institut des Sciences et Ingéniere Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL) , CH-1015 Lausanne , Switzerland.
Abstract:
Gadolinium(III) complexes have recently been demonstrated to have potential as polarizing agents for high-field dynamic nuclear polarization (DNP) NMR spectroscopy. By tailoring the ligand design to reduce the zero-field splitting (ZFS), we demonstrate a quadratic improvement in DNP through the investigation of a stable, water-soluble, narrow-line Gd(III) complex, [Gd(tpatcn)], doubling the magic-angle-spinning DNP enhancement of the previous state-of-the-art [Gd(dota)(H2O)]- at 9.4 T and 100 K.
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