Related Experiment Video
Updated: Jan 24, 2026

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
Published on: December 23, 2016
Palladium(II) Ion Mediated Disulfide/Thiolate Interconversion: Predicting the Disulfide Group State from First
Alexander I Petrov1, Vsevolod D Dergachev2,3
1Institute of Chemistry and Chemical Technology SB RAS , Federal Research Center "Krasnoyarsk Science Center SB RAS" , Krasnoyarsk 660014 , Russian Federation.
Abstract:
Different reactivity of homologous disulfides toward Pd2+ was previously reported: stepwise complexation to Pd2+ for l-cystine and cystamine ligands, while for dl-homocystine and 3,3'-dithiodipropionic acid, disulfide's disproportionation toward thiolate and sulfinic acid complexes is observed. The disulfide/thiolate interconversion of four different disulfide ligands in the presence of nonredox metal cation Pd2+ in aqueous solution has been computationally investigated. We see this different reactivity in different capacities of considered homologous disulfides to stabilize forming S,S'-binuclear complexes, which are believed to be key intermediates toward interconversion products. We thus devise a theoretical model that rationalizes experimentally observed phenomenon of disulfides different reactivity toward nonredox transition metal cation Pd2+.
More Related Videos
Related Concept Videos
The Uncertainty Principle
Hardy-Weinberg Principle
Precipitation of Ions
The equation that describes the equilibrium between solid calcium carbonate and its solvated ions is:
Common Ion Effect
Ions and Ionic Charges
Le Chatelier's Principle: Changing Temperature
To understand this phenomenon, consider the elementary reaction:

