Related Experiment Video
Updated: Jan 24, 2026

Isolation of Primary Myofibroblasts from Mouse and Human Colon Tissue
Published on: October 12, 2013
Carinal Resection and Reconstruction for an Obstructing Inflammatory Myofibroblastic Tumor in a Child
James Nawalaniec1, Bhargava Mullapudi2, Wen Jiang3
1School of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Abstract:
Inflammatory myofibroblastic tumor (IMT) is a rare soft tissue tumor characterized by proliferation of fibroblastic cells associated with an inflammatory infiltrate. Inflammatory myofibroblastic tumors have a predilection for the pediatric population and are usually found in the lung parenchyma but rarely at the carina. They rarely metastasize but can be locally destructive. Surgical resection is the cornerstone of therapy, which results in excellent survival despite risk of local recurrence. We present the case of a nine-year-old girl with an IMT mass at the carina and obstructing the left main stem bronchus, requiring extensive resection and reconstruction.
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