Related Experiment Video
Updated: Jan 24, 2026

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
Published on: November 30, 2016
Giant intrathoracic teratoma presenting with cachexia and severe dyspnea
Emma Ryan1,2, Hani Shennib3,4, Sanjeev Gopal5
1Department of Surgery, University of Arizona, College of Medicine, Phoenix, AZ, USA. emoran602@gmail.com.
Background:
This case highlights the challenges of preoperative differential diagnosis and management in a patient with an uncommon clinical presentation of giant intrathoracic teratoma. The age of the patient, location and size of the tumor, and clinical presentation makes this case unique. Typically, intrathoracic teratomas are found between the ages of 20-30, they are located in the anterior mediastinum, and tumors larger than 25 cm clinically present with cough or dysphagia.
Case Presentation:
A giant intrathoracic teratoma presents in a 51-year-old female as a mid to posterior mediastinal mass compressing the whole left lung with symptoms of depression, anorexia, unintentional weight loss, and cachexia. Due to her severe deconditioning she was optimized for 1 month in a skilled nursing facility with aggressive physical therapy and enteral nutrition. She underwent left thoracotomy with complete resection of the tumor. In follow up her BMI had improved, and she was regaining strength.
Conclusions:
Complete resection was achieved via left thoracotomy after aggressive rehabilitation.
Related Concept Videos
Polytene Chromosomes
Lampbrush Chromosomes
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops...
Light Acquisition
Global Climate Change
Empathy

