Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Interdisciplinary Care: The Health Care Team-I01:21

Interdisciplinary Care: The Health Care Team-I

2.6K
An interdisciplinary team includes many healthcare professionals working together and utilizing their skills, knowledge, and expertise to provide holistic and quality patient care.
Physicians
The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution...
2.6K
Interdisciplinary Care: The Health Care Team-II01:18

Interdisciplinary Care: The Health Care Team-II

2.2K
An interdisciplinary team includes many healthcare professionals working together and utilizing their skills, knowledge, and expertise to provide holistic and quality patient care. Here are a few more healthcare professionals.
Physical Therapist
A physical therapist (PT) aims to restore function or prevent additional impairment in a patient following an injury or disease. Massage, heat, cold, water, sonar waves, exercises, and electrical stimulation are some treatments used by PTs to treat...
2.2K
Optimal Foraging00:48

Optimal Foraging

13.7K
How animals obtain and eat their food is called foraging behavior. Foraging can include searching for plants and hunting for prey and depends on the species and environment.
13.7K
Standards of Care I01:22

Standards of Care I

1.1K
Federal statutes profoundly impact nursing practice, providing critical guidelines to ensure patient care is equitable, accessible, and of the highest quality. The following laws address distinct aspects of healthcare provision and patient rights:
1.1K
Continuing Care01:25

Continuing Care

1.9K
Continuing care describes the variety of health, personal, and social services provided over a prolonged period. The need for continuing care is increasing because people are living longer. Many people do not have families or others to care for them. Continuing care is mainly for patients who are disabled, functionally dependent, or suffering from a terminal disease. It is available within institutional settings or in homes. Examples include nursing centers or facilities, assisted living,...
1.9K
Parental Care00:55

Parental Care

12.7K
Many animals exhibit parental care behavior, including feeding, grooming, and protecting young offspring. Parental care is universal in mammals and birds, which often have young that are born relatively helpless. Several species of insects and fish, as well as some amphibians, also care for their young.
12.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Contribution of fluorodeoxyglucose positron-emission tomography combined with magnetic resonance imaging for differential diagnosis between radionecrosis and recurrence of treated brain metastasis.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2026
Same author

Surface-guided analysis of breast shape changes during postoperative radiotherapy by using a functional map framework.

Medical physics·2026
Same author

From relapse to survival: real-world clinical impact of a multimodal approach in first-time recurrent glioblastoma : FROST: multimodal treatment for GBM recurrence.

Journal of neuro-oncology·2026
Same author

Performance of a Vendor System for Systematic Offline Adaptive Breast Helical Radiotherapy.

Cancers·2026
Same author

Dose-dependent cerebrovascular impact of pediatric brain radiotherapy revealed by advanced MRI: the AVARTHEC study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Tenascin-C orchestrates radiotherapy-induced head and neck tumor regression.

EMBO molecular medicine·2026

Related Experiment Video

Updated: Jan 24, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

953

Medulloblastoma: optimizing care with a multidisciplinary approach.

Alice Thomas1, Georges Noël1,2

  • 1Radiotherapy Department, Centre Paul Strauss, UNICANCER, F-67065 Strasbourg, France, gnoel@strasbourg.unicancer.fr.

Journal of Multidisciplinary Healthcare
|May 24, 2019
PubMed
Summary

Medulloblastoma, a common childhood brain tumor, has seen improved understanding through molecular subgrouping. New targeted therapies and refined radiation strategies offer hope for better outcomes and reduced side effects.

Keywords:
molecular subgroupproton therapyradiotherapytargeted therapies

More Related Videos

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

1.9K
Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice
05:10

Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice

Published on: October 3, 2010

12.6K

Related Experiment Videos

Last Updated: Jan 24, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

953
Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

1.9K
Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice
05:10

Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice

Published on: October 3, 2010

12.6K

Area of Science:

  • Pediatric oncology
  • Neuro-oncology
  • Cancer molecular biology

Background:

  • Medulloblastoma is the most common malignant pediatric brain tumor, originating in the cerebellum.
  • Current treatments (surgery, craniospinal irradiation, chemotherapy) yield ~70% survival but cause significant long-term morbidity.
  • Recent advances have dramatically improved molecular understanding, identifying four prognostic subgroups (WNT, SHH, Group 3, Group 4).

Purpose of the Study:

  • To provide an overview of medulloblastoma through a molecular lens.
  • To discuss evolving therapeutic strategies in surgery, radiotherapy, and targeted therapies.
  • To highlight the potential for optimizing medulloblastoma treatment via a multidisciplinary approach.

Main Methods:

  • Review of current knowledge on medulloblastoma pathophysiology.
  • Analysis of molecular subgroupings and their clinical implications.
  • Discussion of emerging therapeutic modalities and treatment optimization strategies.

Main Results:

  • Molecular advancements have redefined medulloblastoma classification into four distinct prognostic subgroups.
  • Targeted therapies are emerging based on molecular understanding.
  • Personalized radiotherapy approaches are being developed to minimize toxicity.

Conclusions:

  • Molecular insights are revolutionizing medulloblastoma treatment paradigms.
  • Optimized, multidisciplinary approaches incorporating molecular subgroups hold promise for improved survival and reduced morbidity.
  • Future directions focus on refining targeted therapies and radiotherapy for better patient outcomes.