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The Relationship between Sleep Disturbance, Quality of Life and Psychosocial Functioning in Pediatric Patients with
Chaowapong Jarasvaraparn1, Kimberly Zlomke2, Noelle C Vann2
1Department of Pediatrics, University of South Alabama, Mobile, Alabama, USA.
Insights
Sleep disturbance negatively impacts quality of life (QoL) and psychosocial functioning in pediatric patients with inflammatory bowel disease (IBD). Improving sleep can enhance QoL for these children.
Area of Science:
- Pediatric Gastroenterology
- Sleep Medicine
- Child Psychology
Background:
- Pediatric inflammatory bowel disease (IBD) is linked to psychiatric symptoms affecting quality of life (QoL) and psychosocial functioning.
- Sleep disturbance can exacerbate inflammation and negatively impact immune responses.
- The study investigated the interplay between sleep, QoL, and psychosocial well-being in children with IBD.
Purpose of the Study:
- To assess the relationship between sleep disturbance, QoL, and psychosocial functioning in pediatric IBD patients.
- To compare QoL and psychosocial functioning between pediatric IBD subtypes (Crohn's disease vs. ulcerative colitis) and healthy controls.
Main Methods:
- Pediatric IBD patients and their parents completed validated questionnaires on sleep, daytime functioning, QoL, and psychosocial status.
- Health-related QoL (HRQOL) outcomes for IBD patients were compared to a healthy control group.
Main Results:
- A significant positive association was found between sleep quality and QoL in pediatric IBD patients (r = -0.62, p < 0.001).
- Poorer sleep quality and increased daytime sleepiness correlated with lower QoL.
- Patients with Crohn's disease reported better QoL and psychosocial functioning than those with ulcerative colitis; IBD patient QoL was comparable to healthy controls.
Conclusions:
- Sleep functioning is positively associated with QoL in children with IBD.
- Screening for sleep disturbance, QoL, and psychosocial functioning is recommended for pediatric IBD patients.
- Developing interventions for sleep disturbance may improve QoL and psychosocial outcomes in this population.
Background:
Pediatric patients with inflammatory bowel disease (IBD) are at risk for psychiatric symptoms that impact quality of life (QoL) and psychosocial functioning. Sleep disturbance has been reported to impose adverse effects on host defense mechanisms by affecting the magnitude and characteristics of the inflammatory response. The current study sought to assess the relationships among sleep disturbance, QoL, and psychosocial functioning in children with IBD.
Methods:
Pediatric IBD patients completed multiple measures of sleep and daytime functioning as well as measures of QoL and psychosocial functioning. The parents completed complementary measures of sleep, QoL, and psychosocial functioning. The HRQOL results for subjects with IBD were compared to a healthy control group.
Results:
Fifty-three children with pediatric IBD and their parents were enrolled in the study. QoL was positively associated with sleep quality, based on significant negative correlations between QoL and both sleep quality and daytime sleepiness scales (r = -0.62, -0.57; p value <0.001, respectively). Patients with CD reported significantly better QoL and psychosocial functioning than patients with UC. The QoL was similar between IBD patients and healthy controls.
Conclusions:
The present study suggests that a positive association exists between sleep functioning and QoL in pediatric patients with IBD. Patients with pediatric IBD should be screened for sleep disturbance, QoL and psychosocial functioning. Prevention and intervention strategies of sleep disturbance aimed at improving QoL and psychosocial functioning in children with IBD should be developed and evaluated.
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