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Updated: Jan 24, 2026

Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation
Published on: March 15, 2020
Clinical outcomes after AF cardioversion in patients presenting left atrial sludge in trans-esophageal
Fabien Squara1, Mikael Bres2, Didier Scarlatti2
1Hôpital Pasteur, Service de Cardiologie, 30 avenue de la Voie Romaine, CS 51069 06001, Nice Cedex 1, France. fabiensquara@gmail.com.
Insights
Direct-current cardioversion (DCC) for atrial fibrillation is safe even with atrial sludge if no left atrial appendage thrombus is present. This finding supports current guidelines, advising against cardioversion only when atrial thrombus is confirmed.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Imaging
Background:
- Direct-current cardioversion (DCC) for atrial fibrillation (AF) carries a stroke risk, potentially due to post-cardioversion atrial stunning.
- Cardiac thrombus, typically in the left atrial appendage (LAA), is a contraindication for DCC.
- Atrial sludge without LAA thrombus is often considered a relative contraindication, prompting further investigation.
Purpose of the Study:
- To evaluate the safety of DCC in patients with atrial fibrillation who exhibit atrial sludge but no LAA thrombus.
Main Methods:
- Prospective inclusion of consecutive patients with atrial sludge (no LAA thrombus) undergoing DCC for persistent AF.
- Safety assessment focused on clinical events within 1 month post-cardioversion, covering the atrial stunning period.
- Clinical examination and the Questionnaire for Verifying Stroke-Free Status (QVSFS) were used for evaluation.
Main Results:
- Twenty-one patients with atrial sludge but no LAA thrombus underwent DCC over 2 years.
- No clinical embolic or cardiac events, or unscheduled hospitalizations occurred within the 1-month follow-up.
- Sixty-seven percent of patients maintained sinus rhythm at the 1-month follow-up.
Conclusions:
- Direct-current cardioversion for atrial fibrillation is safe in patients with atrial sludge but without left atrial appendage thrombus.
- Findings support current guidelines classifying only atrial thrombus as a contraindication for cardioversion.
- Larger studies are recommended to further validate these results.
Background:
Direct-current cardioversion (DCC) for atrial fibrillation carries a risk of stroke, probably associated with the temporary atrial stunning following cardioversion. The presence of a cardiac thrombus, usually localized in the left atrial appendage (LAA), is recognized as a clear contra-indication to the cardioversion. However, the presence of atrial sludge without LAA thrombus in trans-esophageal echocardiography (TEE) remains, for many cardiologists, a relative contra-indication to the cardioversion. The aim of this study was to evaluate the safety of DCC in patients presenting atrial sludge without LAA thrombus.
Methods:
We prospectively included all consecutive patients demonstrating atrial sludge without LAA thrombus in TEE and undergoing DCC for persistent atrial fibrillation (AF). Safety of DCC was evaluated by the occurrence of clinical events at 1 month following cardioversion, i.e., up to the end of the atrial stunning period, as assessed by clinical examination and the standardized and validated Questionnaire for Verifying Stroke-Free Status (QVSFS).
Results:
Over a period of 2 years, 21 patients presenting atrial sludge without LAA thrombus underwent DCC for AF. During the follow-up period of 1 month after DCC, no clinical embolic event, cardiac event, or unscheduled consultations/hospitalizations occurred. At 1 month, 67% of the patients remained in sinus rhythm.
Conclusion:
No clinical event occurred in patients demonstrating atrial sludge without thrombus and undergoing DCC for AF. These findings support current guidelines that only keep atrial thrombus as a contraindication to cardioversion, but warrant further investigation in large studies.
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