Some Considerations on the WHO Histological Classification of Laryngeal Neoplasms

Area of Science:

• Pathology
• Otolaryngology
• Oncology

Background:

• The 2017 World Health Organization (WHO) Histological Classification of Tumours of the Hypopharynx, Larynx, Trachea and Parapharyngeal Space was released.
• Previous WHO classifications (e.g., 2005) included a broader range of laryngeal neoplasms.

Purpose of the Study:

• To review the 2017 WHO classification specifically for laryngeal neoplasms.
• To discuss the rationale behind the revisions in the classification.
• To highlight the potential impact of omissions on the understanding of laryngeal tumor entities.

Main Methods:

• Review of the 2017 WHO classification.
• Comparative analysis with the 2005 WHO classification.
• Literature review of laryngeal neoplasms.

Main Results:

• The 2017 WHO classification omits several laryngeal neoplasms previously described.
• Some omitted entities are discussed in other sections of the 2017 WHO book.
• This omission may create a false impression regarding the existence of certain laryngeal tumor entities.

Conclusions:

• The revised classification may lead to underrecognition of specific laryngeal neoplasms.
• Pathologists, surgeons, and oncologists need to be aware of these omissions.
• Further clarification or context may be needed for the accurate diagnosis and management of laryngeal tumors.