Related Experiment Video
Updated: Jan 24, 2026
07:27
Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
Published on: December 18, 2012
12.4K
[Infectious keratitis in contact lens wearers]
Cathrien A Eggink1,2, Claudy Oliveira Dos Santos3, Anna C Randag4
1Radboudumc, afd. Oogheelkunde, Nijmegen.
Nederlands Tijdschrift Voor Geneeskunde
|May 24, 2019
Summary
Infectious keratitis, a serious eye infection in contact lens wearers, can be caused by bacteria, fungi, or Acanthamoeba. Prompt ophthalmologist referral and diagnosis are crucial for effective treatment and preventing vision loss.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Infectious keratitis is a significant cause of vision impairment in contact lens users.
- Bacterial pathogens, particularly Pseudomonas aeruginosa, are common culprits.
- Increasing incidences of fungal and Acanthamoeba keratitis are observed.
Observation:
- Case A: An 11-year-old male presented with delayed diagnosis of Acanthamoeba keratitis despite prolonged treatment.
- Case B: A 45-year-old female rapidly developed a severe corneal ulcer due to Pseudomonas aeruginosa.
- Case C: A 27-year-old female exhibited signs typical of fungal keratitis, including satellite infiltrates.
Findings:
- Characteristic clinical signs aid in differentiating causative agents: dentritiform lesions suggest Acanthamoeba, while satellite infiltrates indicate fungal keratitis.
- Contact lens wear is a critical risk factor for infectious keratitis.
- Microbiological diagnostics are essential for accurate identification of the pathogen.
Implications:
- Urgent referral to an ophthalmologist is mandatory for all keratitis patients, especially those with infiltrates.
- Ophthalmologists should confirm the causative agent before prescribing treatments like steroids.
- Early recognition and appropriate management are key to preserving vision in contact lens-related infectious keratitis.
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