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Related Concept Videos

Dementia01:30

Dementia

541
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
541
What is Gene Expression?01:42

What is Gene Expression?

195.2K
Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
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What is Gene Expression?01:36

What is Gene Expression?

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A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is comprised  of nucleotides and proteins are comprised of amino acids, a mediator is required to convert the information encoded in DNA into proteins. This mediator is the messenger RNA (mRNA). mRNA copies the blueprint from DNA by a process called transcription. In eukaryotes, transcription occurs in the nucleus by complementary base-pairing with the DNA template. The mRNA is then...
11.2K
Expressing Solution Concentration02:48

Expressing Solution Concentration

66.1K
A solute is a component of a solution that is typically present at a much lower concentration than the solvent. Solute concentrations are often described with qualitative terms such as dilute (of relatively low concentration) and concentrated (of relatively high concentration).
Concentrations may be quantitatively assessed using a wide variety of measurement units, each convenient for particular applications. Molarity (M) is a useful concentration unit for many applications in chemistry.
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Cell Specific Gene Expression01:58

Cell Specific Gene Expression

16.3K
Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
16.3K
Chromatin Position Affects Gene Expression02:35

Chromatin Position Affects Gene Expression

24.7K
Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences  access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area. 
Topologically Associated Domains (TADs)
The 3-dimensional positioning of chromatin in the nucleus influences the...
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Related Experiment Video

Updated: Jan 24, 2026

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

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[Dementia expressed in metaphors].

Agnieke W T Broos1,2, Anke J M Oerlemans1, Gert J Olthuis1

  • 1Radboudumc, vakgroep Ethiek van de gezondheidszorg, Nijmegen.

Nederlands Tijdschrift Voor Geneeskunde
|May 24, 2019
PubMed
Summary

People with dementia use diverse metaphors to describe their condition, impacting their quality of life and care. Understanding these metaphors can improve patient experiences and healthcare delivery.

Area of Science:

  • Linguistics
  • Gerontology
  • Healthcare Communication

Background:

  • Metaphors are prevalent in healthcare communication between patients and providers.
  • Metaphorical language significantly influences patient perceptions of quality of life and care.
  • Societal metaphors surrounding dementia are often negative, shaping public perception.

Purpose of the Study:

  • To explore the metaphors used by individuals with dementia to describe their lived experiences.
  • To understand how these self-generated metaphors relate to their perception of illness and care.

Main Methods:

  • Qualitative analysis of patient narratives.
  • Thematic identification of metaphorical language used by people with dementia.

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A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis
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A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis

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The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
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The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
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Main Results:

  • Individuals with dementia employ a wide range of metaphors to articulate their experiences with the disease.
  • These metaphors offer unique insights into the subjective reality of living with dementia.

Conclusions:

  • Increased awareness of patient- and clinician-generated metaphors can enhance understanding of the dementia experience.
  • Healthcare providers' sensitivity to metaphorical language can lead to more personalized and effective care strategies for dementia patients.