Related Experiment Video

Updated: Jan 24, 2026

Anterior Cervical Discectomy and Fusion in the Ovine Model
06:11

Anterior Cervical Discectomy and Fusion in the Ovine Model

Published on: October 5, 2009

13.3K

Postcoital bleeding is a predictor for cervical dysplasia

Omer Cohen1, Edwardo Schejter2, Regina Agizim1,2

  • 1Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel.

Plos One
|May 24, 2019
PubMed

Insights

Postcoital bleeding (PCB) may indicate cervical dysplasia, particularly in women with abnormal Pap smears. Colposcopy is recommended, especially for nulliparous women, to assess risk factors for cervical cancer.

Area of Science:

  • Gynecology
  • Oncology
  • Pathology

Background:

  • Postcoital bleeding (PCB) is a frequent gynecological complaint with unclear management guidelines.
  • Existing literature lacks definitive recommendations for evaluating PCB.

Purpose of the Study:

  • To determine risk factors for cervical dysplasia and cancer in patients experiencing postcoital bleeding (PCB).
  • To identify specific patient characteristics associated with adverse cervical pathology following PCB.

Main Methods:

  • A retrospective review of 411 women with PCB from a large health maintenance organization (HMO) database (2012-2015).
  • Data collected included patient demographics, obstetric history, BMI, smoking status, Pap smear results, colposcopy, and biopsy findings.
  • Cases were matched by age and socioeconomic status to controls undergoing routine care.

Main Results:

  • PCB incidence was highest in women aged 26-30.
  • Of 411 PCB cases, 48.9% underwent biopsy, revealing cervicitis (33.8%), CIN 1/koilocytosis (30.3%), and cervical polyps (12.4%).
  • Multiparous women had reduced risk (OR 0.39), while abnormal Pap smears significantly increased risk (OR 3.3) for CIN 1 or higher.
  • PCB patients were more likely to have CIN 1 or higher pathology (OR 1.82) compared to controls.

Conclusions:

  • Postcoital bleeding (PCB) warrants further investigation, including colposcopy, particularly in nulliparous women.
  • An abnormal Pap smear in conjunction with PCB is a significant risk factor for cervical dysplasia.
  • Multiparous status appears protective against significant cervical pathology in PCB patients.
Abstract

More Related Videos

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice08:13

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

7.4K
Surgical Technique for Superior Cervical Ganglionectomy in a Murine Model07:30

Surgical Technique for Superior Cervical Ganglionectomy in a Murine Model

Published on: December 2, 2022

7.1K

Related Concept Videos

Bleeding in Fresh Concrete01:22

Bleeding in Fresh Concrete

Bleeding in fresh concrete occurs when water from the mix rises to the surface. This happens because the mix's solid components fail to retain all the water as they settle, leading to separation where water collects at the top. The severity of bleeding can be measured by assessing the total settlement or by noting the decrease in height per unit height of concrete.
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
560
Chromatin Position Affects Gene Expression02:35

Chromatin Position Affects Gene Expression

Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences  access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area. 
Topologically Associated Domains (TADs)
The 3-dimensional positioning of chromatin in the nucleus influences the...
24.7K