Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Statistical Package for the Social Sciences (SPSS)01:22

Statistical Package for the Social Sciences (SPSS)

1.2K
The Statistical Package for the Social Sciences, or SPSS, is a data management and analysis software suite. Developed by SPSS Inc. in 1968 and acquired by IBM in 2009, this tool was initially designed for social science data analysis, evolving to serve a wider range of disciplines. It was later renamed to Statistical Product and Service Solutions.
SPSS streamlines the process from data preparation to analysis and reporting. It is characterized by its user-friendly interface, which conceals...
1.2K
Combinatorial Gene Control02:33

Combinatorial Gene Control

9.5K
Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
9.5K
DNA Packaging00:58

DNA Packaging

112.2K
Overview
112.2K
Chromatin Packaging01:32

Chromatin Packaging

19.0K
Each human somatic cell contains 6 billion base pairs of DNA. Each base pair is 0.34 nm long, meaning each diploid cell contains a staggering 2 meters of DNA. This long DNA strand is packed inside a nucleus measuring only 10-20 microns in diameter with the help of specialized DNA-binding proteins called histones. Together they form a compact DNA-protein complex called chromatin. The chromatin is further compacted into higher-order structures. The highest level of compaction is achieved during...
19.0K
Chromatin Packaging02:21

Chromatin Packaging

21.9K
Each human somatic cell contains 6 billion base-pairs of DNA. Each base-pair is 0.34 nm long, which means that each diploid cell contains a staggering 2 meters of DNA. How is such a long DNA strand packed inside a nucleus measuring only 10 - 20 microns in diameter? 
The chromatin
In combination with specialized DNA binding protein called Histones, the DNA double helix forms a compact DNA: protein complex called chromatin. The chromatin itself is further compacted into higher-order...
21.9K
Chromatin Packaging02:21

Chromatin Packaging

9.6K
9.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multiscale Characterization of Electrode-Induced Degradation in Perovskite Solar Cells.

ACS applied energy materials·2026
Same author

Phase Diagrams and Piezoelectric Properties of Wurtzite Al<sub>1-x-y</sub>Sc<sub>x</sub>Gd<sub>y</sub>N Heterostructural Alloys.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Heterogeneous doping via nanoscale coating impacts the mechanics of Li intrusion in brittle solid electrolytes.

Nature materials·2026
Same author

Map of the Zintl AM<sub>2</sub>Pn<sub>2</sub> Compounds: Influence of Chemistry on Stability and Electronic Structure.

Chemistry of materials : a publication of the American Chemical Society·2025
Same author

ZnTiN<sub>2</sub> as an Electron-Selective, Protective Layer on Si Photocathodes.

ACS electrochemistry·2025
Same author

Ion Exchange Synthesizes a Metastable Layered Polymorph of MgZrN<sub>2</sub> and MgHfN<sub>2</sub> Semiconductors.

Chemistry of materials : a publication of the American Chemical Society·2025
Same journal

<i>ACS Combinatorial Science:</i> January, 1999-December, 2020.

ACS combinatorial science·2020
Same journal

Aldol Reactions of Biorenewable Triacetic Acid Lactone Precursor Evaluated Using Desorption Electrospray Ionization Mass Spectrometry High-Throughput Experimentation and Validated by Continuous Flow Synthesis.

ACS combinatorial science·2020
Same journal

Fe<sub>3</sub>O<sub>4</sub>@GlcA@Cu-MOF: A Magnetic Metal-Organic Framework as a Recoverable Catalyst for the Hydration of Nitriles and Reduction of Isothiocyanates, Isocyanates, and Isocyanides.

ACS combinatorial science·2020
Same journal

Expanding the Chemical Diversity of Genetically Encoded Libraries.

ACS combinatorial science·2020
Same journal

High-Throughput Characterization of (Fe<sub></sub>Co<sub>1-</sub>)<sub>3</sub>O<sub>4</sub> Thin-Film Composition Spreads.

ACS combinatorial science·2020
Same journal

High Throughput Synthesis and Screening of Oxygen Reduction Catalysts in the <i>M</i>TiO<sub>3</sub> (<i>M</i> = Ca, Sr, Ba) Perovskite Phase Diagram.

ACS combinatorial science·2020
See all related articles

Related Experiment Video

Updated: Jan 24, 2026

Project-Based Learning Guidelines for Health Sciences Students: An Analysis with Data Mining and Qualitative Techniques
13:44

Project-Based Learning Guidelines for Health Sciences Students: An Analysis with Data Mining and Qualitative Techniques

Published on: December 9, 2022

4.2K

COMBIgor: Data-Analysis Package for Combinatorial Materials Science.

Kevin R Talley1,2, Sage R Bauers1, Celeste L Melamed1,3

  • 1National Renewable Energy Laboratory , 15013 Denver West Parkway , Golden , Colorado 80401 , United States.

ACS Combinatorial Science
|May 24, 2019
PubMed
Summary
This summary is machine-generated.

COMBIgor is a new open-source software package designed to streamline data management for combinatorial experiments. This tool simplifies processing and visualizing complex data sets, reducing the burden on scientists.

Keywords:
Igor Procombinatorial librariesdata analysishigh-throughput experimentsproperty mappingsoftwarethin films

More Related Videos

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

33.6K
Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
11:44

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis

Published on: March 30, 2019

8.0K

Related Experiment Videos

Last Updated: Jan 24, 2026

Project-Based Learning Guidelines for Health Sciences Students: An Analysis with Data Mining and Qualitative Techniques
13:44

Project-Based Learning Guidelines for Health Sciences Students: An Analysis with Data Mining and Qualitative Techniques

Published on: December 9, 2022

4.2K
Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

33.6K
Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
11:44

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis

Published on: March 30, 2019

8.0K

Area of Science:

  • Materials Science
  • Data Science
  • Scientific Software Development

Background:

  • Combinatorial experiments generate large, complex datasets requiring advanced analysis.
  • Existing generic software struggles with processing and cross-correlating diverse measurement data.
  • Effective data science is crucial for extracting knowledge from combinatorial studies.

Purpose of the Study:

  • To introduce COMBIgor, a purpose-built open-source software package for managing combinatorial data.
  • To provide a systematic approach for loading, storing, processing, and visualizing combinatorial data.
  • To reduce the data management burden on combinatorial scientists.

Main Methods:

  • Development of COMBIgor, an open-source software package within the Igor Pro environment.
  • Implementation of routines for data loading, storage, and processing from combinatorial libraries.
  • Integration of data analysis and visualization features for figure construction.

Main Results:

  • COMBIgor offers a systematic approach to handle diverse combinatorial data.
  • The software includes methods for data loading, processing, and visualization.
  • COMBIgor is designed for customization to integrate various instruments and algorithms.

Conclusions:

  • COMBIgor significantly reduces the data management burden in combinatorial science.
  • The software facilitates the utilization of large datasets for uncovering new scientific knowledge.
  • COMBIgor's customizable nature makes it adaptable to specific laboratory needs.