Hazard Assessment of Listeria monocytogenes in the Processing of Bovine Milk
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Updated: Jan 24, 2026

Listeria monocytogenes Infection of the Brain
Published on: October 2, 2018
James T Peeler1, V Kelly Bunning2
1Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, 1200 C Street, S.W., Washington, DC 20204.
Abstract:
The steps in Grade A production of bovine milk for human consumption were assessed. A cumulative distribution of values, based on published data, was used to evaluate steps for milking, storage, transportation and pasteurization. Conservative estimates of parameters in the distributions were used to compute concentrations and probabilities. Under normal operations, the probability was less than 2 in 100 that one Listeria monocytogenes cell occurs in every 2 gallons of milk processed at exactly 71.7°C for 15 s. The probability was less than 2 in 100 that one cell occurs in 3.8 × 1010 gallons processed at 74.4°C for 20 s.
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