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Bi-specific monoclonal antibodies: selective binding and complement fixation to cells that express two different

J T Wong, R B Colvin

    Journal of Immunology (Baltimore, Md. : 1950)
    |August 15, 1987
    PubMed
    Summary

    Bispecific monoclonal antibodies (BSMAB) can target cells expressing two antigens, enhancing immunotherapeutic selectivity. These novel antibodies demonstrate significantly improved complement-mediated lysis of dual-antigen-positive cells.

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