Related Experiment Video

Updated: Jan 24, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.5K

A quantitative analysis of CT angiography, large vessel occlusion, and thrombectomy rates in acute ischaemic stroke

E Griffin1, D Herlihy2, R Hayden2

  • 1Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland; Royal College of Surgeons, 123 St Stephens Green, Dublin, Ireland.

Clinical Radiology
|May 25, 2019
PubMed

Insights

Workload for acute computed tomography angiography (CTA) in suspected acute ischemic stroke (AIS) patients was analyzed. Large vessel occlusion (LVO) and thrombectomy rates varied significantly based on stroke diagnosis confirmation, highlighting the need for service planning.

Area of Science:

  • Neurology
  • Radiology
  • Public Health

Background:

  • Acute ischemic stroke (AIS) management relies on rapid diagnosis and intervention.
  • Computed tomography angiography (CTA) is crucial for identifying large vessel occlusion (LVO) in AIS.
  • Stroke center workload and thrombectomy rates require accurate assessment for service provision.

Purpose of the Study:

  • To determine the workload of acute CTA in suspected AIS patients.
  • To analyze rates of LVO and thrombectomy relative to stroke diagnoses.
  • To compare these metrics across three Irish stroke centers.

Main Methods:

  • Retrospective review of CTA data (2015-2017) from three stroke centers.
  • Quantification of CTA studies, LVO, and thrombectomy rates.
  • Correlation with hospital discharge diagnoses (HIPE system).

Main Results:

  • 2,358 acute CTA studies were performed for suspected AIS.
  • LVO rates were 18.4% (suspected AIS), 18.4% (discharge diagnosis), and 40.2% (confirmed AIS).
  • Thrombectomy rates were 12% (suspected AIS), 12% (discharge diagnosis), and 26% (confirmed AIS).

Conclusions:

  • Understanding CTA workload and LVO/thrombectomy rates is vital for stroke service planning.
  • Rates differ significantly based on diagnostic certainty (suspected vs. confirmed AIS).
  • Data is essential for optimizing acute stroke care delivery globally.
Abstract

More Related Videos

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research07:34

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research

Published on: December 15, 2023

3.3K
Permanent Cerebral Vessel Occlusion via Double Ligature and Transection08:22

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

Published on: July 21, 2013

15.6K

Related Concept Videos

Quantitative Analysis01:12

Quantitative Analysis

Quantitative analysis is a technique for measuring the amount of specific constituents in a sample. When the sample's composition is unknown, qualitative analysis is performed first to identify its components, which ensures that the correct substances are measured during the quantitative phase.
In quantitative analysis, two key measurements are made: the sample quantity and a property proportional to the amount of the analyte (the substance being analyzed). This forms the basis of the...
1.4K
Reaction Rate02:53

Reaction Rate

The rate of reaction is the change in the amount of a reactant or product per unit time. Reaction rates are therefore determined by measuring the time dependence of some property that can be related to reactant or product amounts. Rates of reactions that consume or produce gaseous substances, for example, are conveniently determined by measuring changes in volume or pressure.
The mathematical representation of the change in the concentration of reactants and products, over time, is the rate...
62.5K
Speciation Rates01:07

Speciation Rates

Overview
22.7K
Related Rates01:18

Related Rates

When two or more physical quantities are linked by a single relationship, a change in one variable necessarily affects the others. This interdependence forms the basis of related rates analysis, which examines how different quantities change with respect to time. A classic physical example is an expanding balloon, where the size of the balloon changes continuously as air is added.For a hot air balloon, the inflated envelope is commonly idealized as a perfect sphere to simplify mathematical...
45
Measuring Reaction Rates03:09

Measuring Reaction Rates

Polarimetry finds application in chemical kinetics to measure the concentration and reaction kinetics of optically active substances during a chemical reaction. Optically active substances have the capability of rotating the plane of polarization of linearly polarized light passing through them—a feature called optical rotation. Optical activity is attributed to the molecular structure of substances. Normal monochromatic light is unpolarized and possesses oscillations of the electrical...
28.7K
Rate-Determining Steps03:08

Rate-Determining Steps

Relating Reaction Mechanisms
In a multistep reaction mechanism, one of the elementary steps progresses significantly slower than the others. This slowest step is called the rate-limiting step (or rate-determining step). A reaction cannot proceed faster than its slowest step, and hence, the rate-determining step limits the overall reaction rate.
The concept of rate-determining step can be understood from the analogy of a 4-lane freeway with a short-stretch of traffic-bottleneck caused due to...
36.8K