Related Experiment Video
Updated: Jan 24, 2026
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
Prevalence, risk factors and pattern of severe retinopathy of prematurity in eastern Madhya Pradesh
Anamika Dwivedi1, Deepak Dwivedi2, Sujata Lakhtakia1
1Department of Ophthalmology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India.
Insights
This study found a high prevalence of severe retinopathy of prematurity (ROP) in India, with late screening presentation being a key factor in ROP-related blindness. Early detection and intervention are crucial for preventing vision loss in premature infants.
Area of Science:
- Ophthalmology
- Neonatology
- Public Health
Background:
- Retinopathy of prematurity (ROP) is a significant cause of preventable blindness in premature infants.
- Understanding the prevalence and risk factors of severe ROP is crucial for targeted interventions.
Purpose of the Study:
- To determine the prevalence, characteristics, risk factors, and patterns of severe ROP.
- To analyze factors associated with aggressive posterior ROP (APROP) and advanced ROP (stage IV and V).
Main Methods:
- A 5-year retrospective study involving screening of 763 babies.
- Analysis of baseline characteristics, systemic risk factors, and ROP screening findings.
- Statistical analysis using SPSS version 20.
Main Results:
- 30% of screened babies had ROP; 14.2% had severe ROP.
- Low gestational age (GA) and birth weight (BW) were inversely associated with severe ROP.
- Late presentation for screening was the most significant factor for advanced ROP (stage IV and V).
Conclusions:
- High prevalence of severe ROP, including APROP, was observed.
- A notable percentage of severe ROP cases fell outside current screening guidelines.
- Timely screening is critical to prevent ROP-related blindness.
Purpose:
To describe the prevalence, characteristics including risk factors, and pattern of severe ROP from eastern Madhya Pradesh region of India.
Methods:
In this 5-year retrospective study, Baseline characteristics, systemic risk factors, and findings of ROP screening were noted. Factors associated with severe ROP including aggressive posterior ROP (APROP), stage IV and V ROP were analyzed. Statistical analysis was done using SPSS version 20.
Results:
Of 763 babies screened, 30% were diagnosed to have ROP. Prevalence of severe ROP was 14.2% (109) of which 60 (55.5%) were classic and 30 (27.7%) were APROP. Eighteen (16.6%) were diagnosed as advanced ROP (stage IV and V). Mean gestational age (GA) and birth weight (BW) for severe ROP were 31.05 weeks and 1.34 kg, respectively which were inversely associated with severe ROP. But a significant 10% of severe ROP were seen in late preterm babies, >34 weeks. Low GA and respiratory distress syndrome (RDS) were significant risk factors for APROP. Most important factor for stage IV and V ROP was late presentation for screening.
Conclusion:
The study found a high prevalence of severe ROP including APROP. Almost 7% severe ROP cases were outside screening guidelines of NNF. Late presentation for screening is the most important factor associated with ROP related blindness.
Related Concept Videos
01:26Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
01:08Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
01:12Relative Risk
02:16Transcription Factors
01:06Fixed Action Patterns
04:01Factors Affecting Solubility