Related Experiment Video

Updated: Jan 24, 2026

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
06:18

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury

Published on: March 26, 2019

9.5K

Predicting Functional Impairment in patients with chronic subdural hematoma treated with burr hole Trepanation-The

Nicolai Maldaner1, Marketa Sosnova1, Johannes Sarnthein2

  • 1Department of Neurosurgery, University Hospital Zurich & Clinical Neuroscience Center, University of Zurich, Zurich, Switzerland; Department of Neurosurgery, Kantonsspital St.Gallen, St.Gallen, Switzerland.

Clinical Neurology and Neurosurgery
|May 25, 2019
PubMed

Insights

Predicting functional impairment after chronic subdural hematoma (cSDH) surgery is challenging. The new FIT-score, based on motor deficits, age, and disorientation, helps estimate patient recovery and need for support.

Area of Science:

  • Neurosurgery
  • Geriatric Medicine
  • Clinical Outcomes Research

Background:

  • Chronic subdural hematoma (cSDH) treatment with burr hole trepanation can lead to prolonged functional impairment.
  • Accurate prediction of postoperative functional status is crucial for patient management and resource allocation.

Purpose of the Study:

  • To develop and validate a predictive score for functional impairment following burr hole trepanation in cSDH patients.
  • To aid clinicians in counseling patients and families regarding recovery expectations and support needs.

Main Methods:

  • Retrospective analysis of a prospective database of cSDH patients operated between 2013-2016.
  • Development of the Functional Impairment after burr hole Trepanation (FIT-score) using logistic regression based on admission variables.
  • Validation of the FIT-score using Area Under the Receiver-Operating Characteristic (AUROC) curve analysis.

Main Results:

  • A cohort of 253 patients revealed 30% experienced functional impairment (mRS ≥ 2) at follow-up.
  • Severe motor deficits, age (≥85 years), and disorientation at admission were significant predictors of impairment.
  • The FIT-score demonstrated good predictive accuracy with AUROC values of 0.77 for discharge and 0.76 for follow-up.

Conclusions:

  • The FIT-score effectively predicts postoperative functional impairment in cSDH patients treated with burr hole trepanation.
  • This score can assist physicians in patient and family counseling regarding rehabilitation and long-term care planning.
Abstract

Keywords:
AUROCBurr hole trepanationChronic subdural hematomaOutcomeROCScore

More Related Videos

Application of 3D Printing in the Construction of Burr Hole Ring for Deep Brain Stimulation Implants09:02

Application of 3D Printing in the Construction of Burr Hole Ring for Deep Brain Stimulation Implants

Published on: September 7, 2019

7.4K
Assessment of Vascular Function in Patients With Chronic Kidney Disease08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.7K

Related Concept Videos

Induced-fit Model01:13

Induced-fit Model

Most chemical reactions in cells require enzymes—biological catalysts that speed up the reaction without being consumed or permanently changed. They reduce the activation energy needed to convert the reactants into products. Enzymes are proteins, that usually work by binding to a substrate—a reactant molecule that they act upon.
Enzymes exhibit substrate specificity, meaning that they can only bind to certain substrates. This is mainly determined by the shape and chemical...
89.0K
Inclusive Fitness00:57

Inclusive Fitness

Most altruistic behavior—in which one animal helps another at a cost to themselves—occurs between relatives. Scientists think these altruistic behaviors evolved because they increase the inclusive fitness of the animal providing help.
37.8K
Goodness-of-Fit Test01:16

Goodness-of-Fit Test

The goodness-of-fit test is a type of hypothesis test which determines whether the data "fits" a particular distribution. For example, one may suspect that some anonymous data may fit a binomial distribution. A chi-square test (meaning the distribution for the hypothesis test is chi-square) can be used to determine if there is a fit. The null and alternative hypotheses may be written in sentences or stated as equations or inequalities. The test statistic for a goodness-of-fit test is given as...
8.1K
Introduction to z Scores01:06

Introduction to z Scores

A z score (or standardized value) is measured in units of the standard deviation. It tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
z scores...
11.0K
Introduction to z Scores01:05

Introduction to z Scores

A z score (or standardized value) is measured in units of the standard deviation. It indicates how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
z scores...
1.3K
z Scores and Area Under the Curve01:17

z Scores and Area Under the Curve

z scores are the standardized values obtained after converting a normal distribution into a standard normal distribution. A z score is measured in units of the standard deviation. The z score tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a z score of...
18.4K