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Updated: Jan 24, 2026

Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm
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Thoracic Aortic Dissection Associated with Marijuana Use.

Erica K Mason1, Anthony E Gak2, Joan G Finno1

  • 1Department of Emergency Medicine, Lehigh Valley Health Network, Allentown, Pennsylvania.

The Journal of Emergency Medicine
|May 26, 2019
PubMed
Summary
This summary is machine-generated.

This case report details an aortic dissection in a 56-year-old male temporally linked to marijuana use. This highlights a potential, previously unreported association between cannabis and acute aortic dissection (AD).

Keywords:
THCaortic dissectioncannabisillicit drug usemarijuana

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Area of Science:

  • Cardiology
  • Emergency Medicine
  • Toxicology

Background:

  • Acute aortic dissection (AD) is a critical condition primarily affecting older men, with known risk factors including hypertension and smoking.
  • While associated with stimulants like cocaine and methamphetamine, marijuana's link to AD has not been established.
  • Cannabis use is increasing, necessitating an understanding of its potential cardiovascular effects.

Observation:

  • A 56-year-old male with a family history of aortic disease experienced acute aortic dissection shortly after using marijuana.
  • Symptoms included chest pain, shortness of breath, and diaphoresis; initial diagnostics were unremarkable.
  • CT imaging confirmed extensive aortic dissection from the aortic root to the iliac artery.

Findings:

  • This case presents a potential temporal association between marijuana consumption and acute aortic dissection.
  • The patient's presentation and subsequent diagnosis occurred in close proximity to cannabis use.
  • This represents a novel observation, as prior literature has not reported a link between marijuana and AD.

Implications:

  • Emergency physicians must consider marijuana use as a potential factor in patients presenting with chest pain and suspected aortic dissection.
  • Further research is warranted to elucidate the complex relationship between cannabis and cardiovascular events, including AD.
  • The growing legalization of marijuana necessitates increased awareness of its potential adverse cardiovascular outcomes.