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Design, synthesis and evaluation of antiproliferative activity of fluorinated betulinic acid

Jizhen Li1, Ling-Chu Chang2, Kan-Yen Hsieh3

  • 1Department of Organic Chemistry, College of Chemistry, Jilin University, 2519 Jiefang Road, Changchun 130023, China; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, United States.

Bioorganic & Medicinal Chemistry
|May 26, 2019
PubMed

Keywords:
Antiproliferative activityBetulinic acidFluorine introductionTopoisomerase

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