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Updated: Jan 24, 2026
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Subcellular Fractionation of Primary Chronic Lymphocytic Leukemia Cells to Monitor Nuclear/Cytoplasmic Protein Trafficking
Published on: October 23, 2019
12.1K
When leucocytosis is not leukaemia.
Filip Ionescu1, Nwabundo Anusim1, Vonda Douglas-Nikitin1
1Beaumont Health System, Royal Oak, Michigan, USA.
BMJ Case Reports
|May 27, 2019
Summary
An elderly patient with altered mental status and high white blood cell count was initially suspected of leukemia. However, Clostridium difficile infection leading to toxic megacolon was diagnosed and successfully treated.
Area of Science:
- Internal Medicine
- Gastroenterology
- Hematology
Background:
- Clostridium difficile infection (CDI) can lead to severe complications, including toxic megacolon.
- Altered mental status and hyperleukocytosis in elderly patients can mimic hematological malignancies.
