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Published on: May 11, 2015
Diagnosis of type 2 diabetes using serial fasting plasma glucose versus HbA1c in the primary care setting
1MBBS, MNutrSci, BMedSci, FRACGP, FARGP (Emerg Med), general practitioner and emergency medical officer, People First Health Group, Toowoomba, Qld; St Vincent’s Hospital Toowoomba Emergency Centre, East Toowoomba, Qld. shieldaig.reception@peoplefirsthealthgroup.com.au; admin@tpeg.com.au
Background And Objective:
There are few studies investigating the diagnostic accuracy of type 2 diabetes mellitus (T2DM) by comparing fasting plasma glucose (FPG) with glycated haemoglobin (HbA1c). This proof-of-concept study looked at the correlation between FPG and HbA1c in the early diagnosis of T2DM.
Methods:
A case series of 30 consecutive patients met the criteria for T2DM with FPG (>7 mM) or HbA1c (>6.5%), but not both.
Results:
Average FPG in patients who met that criterion was 7.57 mM ± 0.53 mM (average HbA1c 5.81% ± 0.37%). Average HbA1c in patients meeting that criterion was 6.54% ± 0.05% (average FPG 6.18 mM ± 0.8 mM).
Discussion:
Serial FPG testing may lead to earlier diagnosis of T2DM than by HbA1c. A higher-powered study could confirm this supposition.
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