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Updated: Jan 24, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

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P Wave Indices-Advancing Our Understanding of Atrial Fibrillation-Related Cardiovascular Outcomes

Lin Y Chen1, Elsayed Z Soliman2

  • 1Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, United States.

Frontiers in Cardiovascular Medicine
|May 28, 2019
PubMed

Insights

Atrial fibrillation (AF) increases risks for stroke and sudden cardiac death (SCD). P-wave indices may reveal atrial cardiomyopathy, offering insights into these cardiovascular outcomes.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Atrial Cardiomyopathy

Background:

  • Atrial fibrillation (AF) is linked to significant cardiovascular risks, including ischemic stroke, heart failure, and sudden cardiac death (SCD).
  • The precise mechanisms connecting AF to these adverse outcomes are not fully understood.
  • Emerging evidence points to left atrial (LA) abnormality, or atrial cardiomyopathy, as a potential unifying explanation.

Purpose of the Study:

  • To review P-wave indices (PWIs) as markers of atrial remodeling.
  • To discuss the current understanding of how abnormal PWIs relate to AF-associated cardiovascular events, particularly ischemic stroke and SCD.
  • To propose future research directions for atrial cardiomyopathy.

Main Methods:

  • Literature review focusing on P-wave indices and their association with cardiovascular outcomes in atrial fibrillation.
  • Synthesis of current knowledge on atrial remodeling and its clinical implications.
  • Identification of research gaps and future research avenues.

Main Results:

  • P-wave indices (PWIs) are established indicators of atrial remodeling.
  • Abnormal PWIs are associated with an increased risk of ischemic stroke and sudden cardiac death (SCD) in patients with AF.
  • Atrial cardiomyopathy, reflected by PWIs, is a key factor in AF-related morbidity and mortality.

Conclusions:

  • P-wave indices offer valuable insights into atrial cardiomyopathy and AF-related risks.
  • Further research into PWIs can advance the understanding and management of atrial cardiomyopathy.
  • Integrating PWI assessment may improve risk stratification for cardiovascular events in AF patients.

Keywords:
P wave axisP wave durationP wave indicesatrial fibirillationstroke

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