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[Multiple sclerosis in computer tomography of the brain (author's transl)]
Fortschritte Der Neurologie, Psychiatrie, Und Ihrer Grenzgebiete
|February 1, 1979
Summary
Computerised tomography revealed that encephalomyelitis disseminata often presents with ventricular extension and atrophy, not typical demyelination. When demyelination occurs, it characteristically appears in a periventricular pattern.
Area of Science:
- Neurology
- Radiology
- Pathology
Background:
- Encephalomyelitis disseminata (ED) is a neurological condition.
- Understanding the precise tissue changes in ED is crucial for diagnosis and management.
Purpose of the Study:
- To detail the tissue changes in patients with neurologically established encephalomyelitis disseminata using advanced imaging.
- To characterize the predominant pathological substrate in ED.
Main Methods:
- Detailed examination of tissue changes using computerised tomography (160x160 matrix).
- Study included 28 patients with established neurologically diagnosed ED.
Main Results:
- In most cases, demyelination was not the primary pathological feature.
- Ventricular extension and diffuse atrophy were the leading signs, often without demyelination.
- When demyelination was present, it predominantly followed a periventricular pattern.
Conclusions:
- The typical presentation of encephalomyelitis disseminata may involve ventricular changes and atrophy more than demyelination.
- Periventricular demyelination is a key characteristic when it does occur in ED.