The relationship between the carotid and coronary artery stenosis: a study based on angiography

Lifeng Wang1, Xiaofen He2

  • 1a Department of Neurology, Capital Medical University Affiliated Anzhen Hospital , Beijing , China.

Insights

Angiography revealed a significant link between carotid artery stenosis (CAS) and coronary artery stenosis disease (COAS). More severe CAS correlated with a greater number of affected coronary arteries, highlighting a critical association.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Carotid artery stenosis (CAS) and coronary artery stenosis disease (COAS) are frequently associated.
  • Previous studies relied on non-invasive methods to assess this link.
  • Angiographic evaluation provides a more direct assessment of both conditions.

Purpose of the Study:

  • To investigate the relationship between CAS and COAS using digital subtraction angiography (DSA) and coronary angiography (CAG).
  • To identify independent risk factors for severe COAS.
  • To determine if the severity of CAS correlates with the extent of COAS.

Main Methods:

  • Retrospective analysis of 231 patients undergoing same-day DSA and CAG.
  • Patients stratified by stenosis severity: mild (<50%), moderate (50-69%), severe (70-99%), and occlusion (100%).
  • Correlation and risk factor analysis performed using Spearman and Kendall's tau-b tests.

Main Results:

  • Independent risk factors for severe COAS (≥70%) included age, sex, prior cerebral infarction, coronary heart disease, and coronary artery surgery.
  • A significant association was found between CAS and COAS (Spearman r = 0.333, P < 0.01).
  • Increased severity of CAS was directly correlated with increased COAS involvement (Kendall's tau-b = 0.294, p < 0.01).

Conclusions:

  • Digital subtraction angiography confirmed the association between carotid artery stenosis and coronary artery stenosis disease.
  • The severity of carotid artery stenosis is directly proportional to the number of affected coronary arteries.
  • These findings underscore the importance of considering concurrent coronary artery disease in patients with significant carotid stenosis.

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