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An analysis of central venous catheter-based hemodialysis starts
Insights
Most patients start hemodialysis (HD) with central venous catheters (CVCs), increasing risks. Urgent need in new patients and access issues in those known to nephrology were primary drivers for CVC use.
Area of Science:
- Nephrology
- Vascular Access
- Renal Replacement Therapy
Background:
- Central venous catheters (CVCs) are frequently used for initiating hemodialysis (HD) in the United States.
- CVC use is associated with increased patient morbidity and mortality compared to permanent access.
- Understanding the specific reasons for CVC initiation is crucial for improving patient outcomes.
Purpose of the Study:
- To determine the most common proximate causes for initiating hemodialysis via CVC.
- To quantify the relative frequency of each identified cause for CVC-based HD starts.
Main Methods:
- Retrospective chart review of 136 consecutive patients initiating HD with a CVC.
- Analysis of patient records to identify the primary reason for CVC use at dialysis initiation.
Main Results:
- The most frequent reason for CVC initiation was urgent need in patients previously unknown to nephrology (31%).
- For patients known to nephrology, common reasons included rapid kidney disease progression/acute on CKD (26.4%), non-functioning or immature arteriovenous (AV) access (18.7%, 11%), and lack of AV access due to patient factors (16.5% refusal, 9.9% poor follow-up).
Conclusions:
- Urgent presentation and issues with permanent vascular access (AV fistula/graft) are key drivers for CVC use in hemodialysis.
- Targeted strategies are needed to address these factors and promote the use of permanent access for dialysis initiation.
Abstract:
Most patients in the United States initiate hemodialysis (HD) with a central venous catheter (CVC) despite a significantly increased morbidity and mortality associated with their use. Reasons for CVC-based starts have been identified, but the relative frequency of each is less clear. The aim of this retrospective chart review was to determine the most proximate cause for CVC-based HD initiations, and to determine the relative frequency of each cause. Out of 136 consecutive patients who started HD with a CVC, the most common reason was an urgent need for dialysis in a patient previously unknown to nephrology presenting acutely with end-stage renal disease (31%). Among patients known to nephrology, the most common reasons for a CVC-based start were a more rapid than expected kidney disease progression and/or acute on chronic kidney disease (CKD) (26.4%), a non-working (18.7%) or immature (11%) arteriovenous (AV) access at the time of dialysis initiation, and lack of AV access either due to patient refusal (16.5%) or failure to follow-up with fistula planning appointments (9.9%). Strategies addressing these factors are needed to ensure more patients start dialysis with a permanent access in place.
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