Related Experiment Video
Updated: Jan 24, 2026

Genetic Manipulation in Δku80 Strains for Functional Genomic Analysis of Toxoplasma gondii
Published on: July 12, 2013
Genetic characterization of one duck-origin paramyxovirus type 4 strain in China
Xiaoyuan Yuan1, Kai Meng1, Yuxia Zhang1
1Institute of Poultry Science, Shandong Academy of Agricultural Sciences, Ji'nan, China.
Abstract:
Avian paramyxovirus type 4 (APMV-4) has been frequently reported from wildfowl and waterfowl in recent year. However, few studies have reported on the molecular characteristics and regional transmission of APMV-4, knowledge of which is important for understanding the genetic diversity and epidemiology of avian paramyxovirus. Herein, we report the isolation of one APMV-4 strain, designated as QY17, from the duck in eastern China. The determined complete genome of the isolate with six gene segments 3'-N-P-M-F-HN-L-5' was 15,054 nt in length. Genetic analysis of the whole-fusion gene of this isolate showed that QY17 was derived from a Eurasian lineage. Further phylogenetic analysis showed that the duck-origin strain QY17 had a highly genetic relationship with representative APMV-4 strains from wildfowl in neighbouring regions. These genetic results suggested that APMV-4 viral exchange may occur in wildfowl and poultry via wild bird migration.
Insights
Avian paramyxovirus type 4 (APMV-4) in ducks was analyzed in China. Genetic data suggest APMV-4 spreads between wild birds and poultry through migration, impacting avian paramyxovirus epidemiology.
Area of Science:
- Veterinary Virology
- Molecular Epidemiology
- Avian Infectious Diseases
Background:
- Avian paramyxovirus type 4 (APMV-4) is increasingly detected in wild and domestic birds.
- Limited data exist on APMV-4 molecular characteristics and transmission dynamics.
- Understanding APMV-4 is crucial for avian paramyxovirus genetic diversity and epidemiology.
Purpose of the Study:
- To characterize a novel APMV-4 strain isolated from a duck in China.
- To investigate the genetic lineage and regional transmission of APMV-4.
Main Methods:
- Isolation and complete genome sequencing of an APMV-4 strain (QY17) from a duck.
- Phylogenetic analysis of the fusion gene and whole genome.
Main Results:
- The complete genome of the APMV-4 QY17 strain was determined (15,054 nt).
- QY17 belongs to the Eurasian lineage of APMV-4.
- Phylogenetic analysis revealed close genetic relationships with APMV-4 strains from neighboring wildfowl populations.
Conclusions:
- The duck-origin APMV-4 strain QY17 provides insights into viral genetic diversity.
- Findings suggest potential viral exchange between wild birds and poultry via migration routes.
- This highlights the importance of monitoring APMV-4 in wild bird populations for disease control.
Related Concept Videos
Types of Genetic Transfer Between Organisms
Types of Genetic Transfer Between Organisms
What is Population Genetics?
Genetics of Speciation
What is Genetic Engineering?
Thermal Strain

