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Updated: Jan 24, 2026

Preparation of Functional Silica Using a Bioinspired Method
Published on: August 1, 2018
Silicate-Phenolic Networks: Coordination-Mediated Deposition of Bioinspired Tannic Acid Coatings
Florian Weber1, Wei-Chih Liao2, Alejandro Barrantes1
1Department of Biomaterials, Institute of Clinical Dentistry, University of Oslo, P.O. Box 1109 Blindern, 0317, Oslo, Norway.
Abstract:
Surface modification with polyphenolic molecules has been pursued in biomedical materials owing to their antioxidant, anti-inflammatory, and antimicrobial characteristics. Recently, the use of silicic acid (Siaq ) as a mediator for efficient surface deposition of tannic acid (TA) was reported, but the postulated Si-TA polymeric networks were not characterized. Herein, we present unambiguous evidence for silicate-TA networks that involve Si-O-C motifs by using solid-state NMR spectroscopy, further supported by XPS and ToF-SIMS. By using QCM-D we demonstrate the advantages of Siaq , compared to using transition-metal ions, to improve the coating efficiency under mildly acidic conditions. The presented homogenous coating buildup and validated applicability in inorganic buffers broadens the use of TA for surface modifications in technological and biomedical applications.
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